Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing

The transcription factor Nkx2.5 is essential for heart development. Here, the authors identify a previously unknown expression domain for Nkx2.5 in the emu wing and explore its role in diminished wing bud development in the flightless emu, compared with three other birds that have functional wings.

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Autores principales:	Peter G. Farlie, Nadia M. Davidson, Naomi L. Baker, Mai Raabus, Kelly N. Roeszler, Claire Hirst, Andrew Major, Mylene M. Mariette, David M. Lambert, Alicia Oshlack, Craig A. Smith
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d39fc2c1c3a943f48666365a2d6c0c28
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spelling	oai:doaj.org-article:d39fc2c1c3a943f48666365a2d6c0c282021-12-02T10:47:59ZCo-option of the cardiac transcription factor Nkx2.5 during development of the emu wing10.1038/s41467-017-00112-72041-1723https://doaj.org/article/d39fc2c1c3a943f48666365a2d6c0c282017-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00112-7https://doaj.org/toc/2041-1723The transcription factor Nkx2.5 is essential for heart development. Here, the authors identify a previously unknown expression domain for Nkx2.5 in the emu wing and explore its role in diminished wing bud development in the flightless emu, compared with three other birds that have functional wings.Peter G. FarlieNadia M. DavidsonNaomi L. BakerMai RaabusKelly N. RoeszlerClaire HirstAndrew MajorMylene M. MarietteDavid M. LambertAlicia OshlackCraig A. SmithNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peter G. Farlie Nadia M. Davidson Naomi L. Baker Mai Raabus Kelly N. Roeszler Claire Hirst Andrew Major Mylene M. Mariette David M. Lambert Alicia Oshlack Craig A. Smith Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing
description	The transcription factor Nkx2.5 is essential for heart development. Here, the authors identify a previously unknown expression domain for Nkx2.5 in the emu wing and explore its role in diminished wing bud development in the flightless emu, compared with three other birds that have functional wings.
format	article
author	Peter G. Farlie Nadia M. Davidson Naomi L. Baker Mai Raabus Kelly N. Roeszler Claire Hirst Andrew Major Mylene M. Mariette David M. Lambert Alicia Oshlack Craig A. Smith
author_facet	Peter G. Farlie Nadia M. Davidson Naomi L. Baker Mai Raabus Kelly N. Roeszler Claire Hirst Andrew Major Mylene M. Mariette David M. Lambert Alicia Oshlack Craig A. Smith
author_sort	Peter G. Farlie
title	Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing
title_short	Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing
title_full	Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing
title_fullStr	Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing
title_full_unstemmed	Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing
title_sort	co-option of the cardiac transcription factor nkx2.5 during development of the emu wing
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d39fc2c1c3a943f48666365a2d6c0c28
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Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing

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