The YfiBNR signal transduction mechanism reveals novel targets for the evolution of persistent Pseudomonas aeruginosa in cystic fibrosis airways.

The genetic adaptation of pathogens in host tissue plays a key role in the establishment of chronic infections. While whole genome sequencing has opened up the analysis of genetic changes occurring during long-term infections, the identification and characterization of adaptive traits is often obscu...

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Autores principales: Jacob G Malone, Tina Jaeger, Pablo Manfredi, Andreas Dötsch, Andrea Blanka, Raphael Bos, Guy R Cornelis, Susanne Häussler, Urs Jenal
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/d3a5ad4a8f09455393af0822dc346635
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