Similar NF-κB gene signatures in TNF-α treated human endothelial cells and breast tumor biopsies.
<h4>Background</h4>Endothelial dysfunction has been implicated in the pathogenesis of diverse pathologies ranging from vascular and immune diseases to cancer. TNF-α is one of the mediators of endothelial dysfunction through the activation of transcription factors, including NF-κB. While...
Enregistré dans:
Auteurs principaux: | Martine Perrot-Applanat, Sophie Vacher, Aurore Toullec, Irma Pelaez, Guillaume Velasco, Françoise Cormier, Hanan El Sheikh Saad, Rosette Lidereau, Véronique Baud, Ivan Bièche |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2011
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/d3a99fb0c6ef4f82a7482ab49f89e902 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway.
par: Magdalena Cizkova, et autres
Publié: (2010) -
A network-centric approach to drugging TNF-induced NF-κB signaling
par: Nicolas A. Pabon, et autres
Publié: (2019) -
Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation.
par: Ananthamurthy Nagabhushana, et autres
Publié: (2011) -
IκBα is required for full transcriptional induction of some NFκB-regulated genes in response to TNF in MCF-7 cells
par: Minami Ando, et autres
Publié: (2021) -
The velvet family of fungal regulators contains a DNA-binding domain structurally similar to NF-κB.
par: Yasar Luqman Ahmed, et autres
Publié: (2013)