A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension

During development, organs undergo large scale forces driven by the cytoskeleton but the precise molecular regulation of cytoskeletal networks remains unclear. Here, the authors report a Cdc42-dependent supracellular cytoskeletal network integrates local actomyosin contraction at tissue scale and dr...

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Autores principales:	Anna Popkova, Orrin J. Stone, Lin Chen, Xiang Qin, Chang Liu, Jiaying Liu, Karine Belguise, Denise J. Montell, Klaus M. Hahn, Matteo Rauzi, Xiaobo Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d3b75b595c2245e39bc3c0fe1f6b3ca6
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spelling	oai:doaj.org-article:d3b75b595c2245e39bc3c0fe1f6b3ca62021-12-02T14:41:13ZA Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension10.1038/s41467-020-15593-22041-1723https://doaj.org/article/d3b75b595c2245e39bc3c0fe1f6b3ca62020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15593-2https://doaj.org/toc/2041-1723During development, organs undergo large scale forces driven by the cytoskeleton but the precise molecular regulation of cytoskeletal networks remains unclear. Here, the authors report a Cdc42-dependent supracellular cytoskeletal network integrates local actomyosin contraction at tissue scale and drives global tissue elongation.Anna PopkovaOrrin J. StoneLin ChenXiang QinChang LiuJiaying LiuKarine BelguiseDenise J. MontellKlaus M. HahnMatteo RauziXiaobo WangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anna Popkova Orrin J. Stone Lin Chen Xiang Qin Chang Liu Jiaying Liu Karine Belguise Denise J. Montell Klaus M. Hahn Matteo Rauzi Xiaobo Wang A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension
description	During development, organs undergo large scale forces driven by the cytoskeleton but the precise molecular regulation of cytoskeletal networks remains unclear. Here, the authors report a Cdc42-dependent supracellular cytoskeletal network integrates local actomyosin contraction at tissue scale and drives global tissue elongation.
format	article
author	Anna Popkova Orrin J. Stone Lin Chen Xiang Qin Chang Liu Jiaying Liu Karine Belguise Denise J. Montell Klaus M. Hahn Matteo Rauzi Xiaobo Wang
author_facet	Anna Popkova Orrin J. Stone Lin Chen Xiang Qin Chang Liu Jiaying Liu Karine Belguise Denise J. Montell Klaus M. Hahn Matteo Rauzi Xiaobo Wang
author_sort	Anna Popkova
title	A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension
title_short	A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension
title_full	A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension
title_fullStr	A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension
title_full_unstemmed	A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension
title_sort	cdc42-mediated supracellular network drives polarized forces and drosophila egg chamber extension
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d3b75b595c2245e39bc3c0fe1f6b3ca6
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A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension

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