Single-molecule imaging reveals multiple pathways for the recruitment of translesion polymerases after DNA damage

Single-molecule imaging reveals multiple pathways for the recruitment of translesion polymerases after DNA damage

Translesion synthesis (TLS) enables cells to tolerate damaged DNA encountered during replication. Here the authors use super-resolution photoactivation localization microscopy to reveal a lesion type dependent mechanism of recruitment of the TLS polymerase Pol IV following DNA damage.

Guardado en:
Detalles Bibliográficos
Autores principales: Elizabeth S. Thrall, James E. Kath, Seungwoo Chang, Joseph J. Loparo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/d3bdcb38b59846ff94dc46e555e13faf
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares