The Molecular Structure and Case Fatality Rate of COVID-19

A new coronavirus recognized as 2019 novel coronavirus (COVID-19) is the etiological cause in charge of the 2019-2020 viral pneumonia worldwide outbreak. The molecular structure and genome of this virus are identical to SARA-CoV and for an unknown reason, it is highly transmittable. The spike protei...

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Autores principales:	Zahra Sadat Aghamir, Sepideh Shivarani, Rima Manafi Shabestari
Formato:	article
Lenguaje:	EN
Publicado:	Urology Research Center 2020
Materias:	covid-19 proteins 2019 novel coronavirus case fatality rate Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/d3c181f75bfb4368a7cf62a1908e6d3e
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spelling	oai:doaj.org-article:d3c181f75bfb4368a7cf62a1908e6d3e2021-11-29T07:54:24ZThe Molecular Structure and Case Fatality Rate of COVID-1910.22034/TRU.2021.269615.10602717-042Xhttps://doaj.org/article/d3c181f75bfb4368a7cf62a1908e6d3e2020-08-01T00:00:00Zhttps://www.transresurology.com/article_124716.htmlhttps://doaj.org/toc/2717-042XA new coronavirus recognized as 2019 novel coronavirus (COVID-19) is the etiological cause in charge of the 2019-2020 viral pneumonia worldwide outbreak. The molecular structure and genome of this virus are identical to SARA-CoV and for an unknown reason, it is highly transmittable. The spike protein is responsible to attach to the host cell and viral single-stranded RNA (ssRNA) entrance to the cells. Upon binding of the Spike proteins to the host cell ACE2 receptor and merging with the membrane, COVID-19 ssRNA goes to the host cells. The viral RNAs are recognized as the foreign element by TLR3, TLR7, TLR8, and TLR9 in the host cell. The viral genome receptor retinoic-acid inducible, cytosolic receptor melanoma differentiation-associated gene and nucleotidyltransferase cyclic GMP-AMP synthase (cGAS) is in charge of viral RNA representation in the cytoplasm. Now there is no targeted therapeutics with high efficacies for the treatment of Covid 19 disease. More than usual medication some interfering RNA molecules are under debate. The reason for being high transmission of COVID-19 is not recognized. This virus pandemic is now all over the world. Zahra Sadat AghamirSepideh Shivarani Rima Manafi Shabestari Urology Research Centerarticlecovid-19proteins2019 novel coronaviruscase fatality rateDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 2, Iss 3, Pp 96-106 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	covid-19 proteins 2019 novel coronavirus case fatality rate Diseases of the genitourinary system. Urology RC870-923
spellingShingle	covid-19 proteins 2019 novel coronavirus case fatality rate Diseases of the genitourinary system. Urology RC870-923 Zahra Sadat Aghamir Sepideh Shivarani Rima Manafi Shabestari The Molecular Structure and Case Fatality Rate of COVID-19
description	A new coronavirus recognized as 2019 novel coronavirus (COVID-19) is the etiological cause in charge of the 2019-2020 viral pneumonia worldwide outbreak. The molecular structure and genome of this virus are identical to SARA-CoV and for an unknown reason, it is highly transmittable. The spike protein is responsible to attach to the host cell and viral single-stranded RNA (ssRNA) entrance to the cells. Upon binding of the Spike proteins to the host cell ACE2 receptor and merging with the membrane, COVID-19 ssRNA goes to the host cells. The viral RNAs are recognized as the foreign element by TLR3, TLR7, TLR8, and TLR9 in the host cell. The viral genome receptor retinoic-acid inducible, cytosolic receptor melanoma differentiation-associated gene and nucleotidyltransferase cyclic GMP-AMP synthase (cGAS) is in charge of viral RNA representation in the cytoplasm. Now there is no targeted therapeutics with high efficacies for the treatment of Covid 19 disease. More than usual medication some interfering RNA molecules are under debate. The reason for being high transmission of COVID-19 is not recognized. This virus pandemic is now all over the world.
format	article
author	Zahra Sadat Aghamir Sepideh Shivarani Rima Manafi Shabestari
author_facet	Zahra Sadat Aghamir Sepideh Shivarani Rima Manafi Shabestari
author_sort	Zahra Sadat Aghamir
title	The Molecular Structure and Case Fatality Rate of COVID-19
title_short	The Molecular Structure and Case Fatality Rate of COVID-19
title_full	The Molecular Structure and Case Fatality Rate of COVID-19
title_fullStr	The Molecular Structure and Case Fatality Rate of COVID-19
title_full_unstemmed	The Molecular Structure and Case Fatality Rate of COVID-19
title_sort	molecular structure and case fatality rate of covid-19
publisher	Urology Research Center
publishDate	2020
url	https://doaj.org/article/d3c181f75bfb4368a7cf62a1908e6d3e
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The Molecular Structure and Case Fatality Rate of COVID-19

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