Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum

miRNA profiling from patient blood can be used for cancer diagnosis. Here the authors present an electro-optical nanopore sensing platform which allows sensitive and specific miRNA detection directly in human serum and apply to monitoring of miR-141-3p and miR-375-3p in different stage of prostate c...

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Autores principales:	Shenglin Cai, Thomas Pataillot-Meakin, Akifumi Shibakawa, Ren Ren, Charlotte L. Bevan, Sylvain Ladame, Aleksandar P. Ivanov, Joshua B. Edel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d3c563e3e37e455093e426357d5c1670
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spelling	oai:doaj.org-article:d3c563e3e37e455093e426357d5c16702021-12-02T14:58:23ZSingle-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum10.1038/s41467-021-23497-y2041-1723https://doaj.org/article/d3c563e3e37e455093e426357d5c16702021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23497-yhttps://doaj.org/toc/2041-1723miRNA profiling from patient blood can be used for cancer diagnosis. Here the authors present an electro-optical nanopore sensing platform which allows sensitive and specific miRNA detection directly in human serum and apply to monitoring of miR-141-3p and miR-375-3p in different stage of prostate cancer.Shenglin CaiThomas Pataillot-MeakinAkifumi ShibakawaRen RenCharlotte L. BevanSylvain LadameAleksandar P. IvanovJoshua B. EdelNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shenglin Cai Thomas Pataillot-Meakin Akifumi Shibakawa Ren Ren Charlotte L. Bevan Sylvain Ladame Aleksandar P. Ivanov Joshua B. Edel Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
description	miRNA profiling from patient blood can be used for cancer diagnosis. Here the authors present an electro-optical nanopore sensing platform which allows sensitive and specific miRNA detection directly in human serum and apply to monitoring of miR-141-3p and miR-375-3p in different stage of prostate cancer.
format	article
author	Shenglin Cai Thomas Pataillot-Meakin Akifumi Shibakawa Ren Ren Charlotte L. Bevan Sylvain Ladame Aleksandar P. Ivanov Joshua B. Edel
author_facet	Shenglin Cai Thomas Pataillot-Meakin Akifumi Shibakawa Ren Ren Charlotte L. Bevan Sylvain Ladame Aleksandar P. Ivanov Joshua B. Edel
author_sort	Shenglin Cai
title	Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
title_short	Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
title_full	Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
title_fullStr	Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
title_full_unstemmed	Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
title_sort	single-molecule amplification-free multiplexed detection of circulating microrna cancer biomarkers from serum
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d3c563e3e37e455093e426357d5c1670
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Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum

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