Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions

Measuring growth factors in single cells at physiologically relevant stimulation doses is challenging. Here the authors use fluorescent quantum dots and calibrated three-dimensional deconvolution microscopy to digitally count growth factors in single cells and reveal stimulation distributions in can...

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Autores principales:	Phuong Le, Sung Jun Lim, Brian C. Baculis, Hee Jung Chung, Kristopher A. Kilian, Andrew M. Smith
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d3c5be8c2a3e4caaac6ba0105ccb9d5c
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spelling	oai:doaj.org-article:d3c5be8c2a3e4caaac6ba0105ccb9d5c2021-12-02T14:35:31ZCounting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions10.1038/s41467-019-08754-52041-1723https://doaj.org/article/d3c5be8c2a3e4caaac6ba0105ccb9d5c2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08754-5https://doaj.org/toc/2041-1723Measuring growth factors in single cells at physiologically relevant stimulation doses is challenging. Here the authors use fluorescent quantum dots and calibrated three-dimensional deconvolution microscopy to digitally count growth factors in single cells and reveal stimulation distributions in cancer cells.Phuong LeSung Jun LimBrian C. BaculisHee Jung ChungKristopher A. KilianAndrew M. SmithNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Phuong Le Sung Jun Lim Brian C. Baculis Hee Jung Chung Kristopher A. Kilian Andrew M. Smith Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions
description	Measuring growth factors in single cells at physiologically relevant stimulation doses is challenging. Here the authors use fluorescent quantum dots and calibrated three-dimensional deconvolution microscopy to digitally count growth factors in single cells and reveal stimulation distributions in cancer cells.
format	article
author	Phuong Le Sung Jun Lim Brian C. Baculis Hee Jung Chung Kristopher A. Kilian Andrew M. Smith
author_facet	Phuong Le Sung Jun Lim Brian C. Baculis Hee Jung Chung Kristopher A. Kilian Andrew M. Smith
author_sort	Phuong Le
title	Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions
title_short	Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions
title_full	Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions
title_fullStr	Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions
title_full_unstemmed	Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions
title_sort	counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d3c5be8c2a3e4caaac6ba0105ccb9d5c
work_keys_str_mv	AT phuongle countinggrowthfactorsinsinglecellswithinfraredquantumdotstomeasurediscretestimulationdistributions AT sungjunlim countinggrowthfactorsinsinglecellswithinfraredquantumdotstomeasurediscretestimulationdistributions AT briancbaculis countinggrowthfactorsinsinglecellswithinfraredquantumdotstomeasurediscretestimulationdistributions AT heejungchung countinggrowthfactorsinsinglecellswithinfraredquantumdotstomeasurediscretestimulationdistributions AT kristopherakilian countinggrowthfactorsinsinglecellswithinfraredquantumdotstomeasurediscretestimulationdistributions AT andrewmsmith countinggrowthfactorsinsinglecellswithinfraredquantumdotstomeasurediscretestimulationdistributions
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Counting growth factors in single cells with infrared quantum dots to measure discrete stimulation distributions

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