Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona
Large-scale, unbiased proteomics studies of biological samples like plasma are constrained by the complexity of the proteome. Herein, the authors develop a highly parallel protein quantitation platform leveraging multi nanoparticle protein coronas for deep proteome sampling and biomarker discovery.
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Nature Portfolio
2020
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oai:doaj.org-article:d3c8b28ba0034c5bb30a513f8c83660d2021-12-02T16:18:02ZRapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona10.1038/s41467-020-17033-72041-1723https://doaj.org/article/d3c8b28ba0034c5bb30a513f8c83660d2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17033-7https://doaj.org/toc/2041-1723Large-scale, unbiased proteomics studies of biological samples like plasma are constrained by the complexity of the proteome. Herein, the authors develop a highly parallel protein quantitation platform leveraging multi nanoparticle protein coronas for deep proteome sampling and biomarker discovery.John E. BlumeWilliam C. ManningGregory TroianoDaniel HornburgMichael FigaLyndal HesterbergTheodore L. PlattXiaoyan ZhaoRea A. CuaresmaPatrick A. EverleyMarwin KoHope LiouMax MahoneyShadi FerdosiEltaher M. ElgierariCraig StolarczykBehzad TangeyshHongwei XiaRyan BenzAsim SiddiquiSteven A. CarrPhilip MaRobert LangerVivek FariasOmid C. FarokhzadNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q John E. Blume William C. Manning Gregory Troiano Daniel Hornburg Michael Figa Lyndal Hesterberg Theodore L. Platt Xiaoyan Zhao Rea A. Cuaresma Patrick A. Everley Marwin Ko Hope Liou Max Mahoney Shadi Ferdosi Eltaher M. Elgierari Craig Stolarczyk Behzad Tangeysh Hongwei Xia Ryan Benz Asim Siddiqui Steven A. Carr Philip Ma Robert Langer Vivek Farias Omid C. Farokhzad Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona |
| description |
Large-scale, unbiased proteomics studies of biological samples like plasma are constrained by the complexity of the proteome. Herein, the authors develop a highly parallel protein quantitation platform leveraging multi nanoparticle protein coronas for deep proteome sampling and biomarker discovery. |
| format |
article |
| author |
John E. Blume William C. Manning Gregory Troiano Daniel Hornburg Michael Figa Lyndal Hesterberg Theodore L. Platt Xiaoyan Zhao Rea A. Cuaresma Patrick A. Everley Marwin Ko Hope Liou Max Mahoney Shadi Ferdosi Eltaher M. Elgierari Craig Stolarczyk Behzad Tangeysh Hongwei Xia Ryan Benz Asim Siddiqui Steven A. Carr Philip Ma Robert Langer Vivek Farias Omid C. Farokhzad |
| author_facet |
John E. Blume William C. Manning Gregory Troiano Daniel Hornburg Michael Figa Lyndal Hesterberg Theodore L. Platt Xiaoyan Zhao Rea A. Cuaresma Patrick A. Everley Marwin Ko Hope Liou Max Mahoney Shadi Ferdosi Eltaher M. Elgierari Craig Stolarczyk Behzad Tangeysh Hongwei Xia Ryan Benz Asim Siddiqui Steven A. Carr Philip Ma Robert Langer Vivek Farias Omid C. Farokhzad |
| author_sort |
John E. Blume |
| title |
Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona |
| title_short |
Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona |
| title_full |
Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona |
| title_fullStr |
Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona |
| title_full_unstemmed |
Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona |
| title_sort |
rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/d3c8b28ba0034c5bb30a513f8c83660d |
| work_keys_str_mv |
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