Binding mode analyses and pharmacophore model development for stilbene derivatives as a novel and competitive class of α-glucosidase inhibitors.
Stilbene urea derivatives as a novel and competitive class of non-glycosidic α-glucosidase inhibitors are effective for the treatment of type II diabetes and obesity. The main purposes of our molecular modeling study are to explore the most suitable binding poses of stilbene derivatives with analyzi...
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Auteurs principaux: | Yuno Lee, Songmi Kim, Jun Young Kim, Mahreen Arooj, Siu Kim, Swan Hwang, Byeong-Woo Kim, Ki Hun Park, Keun Woo Lee |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2014
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Accès en ligne: | https://doaj.org/article/d3ce32c651c1477a9d8cc4227adf0de6 |
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