Flexible oxygen concentrators for medical applications

Abstract Medical oxygen concentrators (MOCs) are used for supplying medical grade oxygen to prevent hypoxemia-related complications related to COVID-19, chronic obstructive pulmonary disease (COPD), chronic bronchitis and pneumonia. MOCs often use a technology called pressure swing adsorption (PSA),...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Akhil Arora, M. M. Faruque Hasan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d3d32e36961c4946b1a6e740b35fd3aa
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d3d32e36961c4946b1a6e740b35fd3aa
record_format	dspace
spelling	oai:doaj.org-article:d3d32e36961c4946b1a6e740b35fd3aa2021-12-02T15:33:00ZFlexible oxygen concentrators for medical applications10.1038/s41598-021-93796-32045-2322https://doaj.org/article/d3d32e36961c4946b1a6e740b35fd3aa2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-93796-3https://doaj.org/toc/2045-2322Abstract Medical oxygen concentrators (MOCs) are used for supplying medical grade oxygen to prevent hypoxemia-related complications related to COVID-19, chronic obstructive pulmonary disease (COPD), chronic bronchitis and pneumonia. MOCs often use a technology called pressure swing adsorption (PSA), which relies on nitrogen-selective adsorbents for producing oxygen from ambient air. MOCs are often designed for fixed product specifications, thereby limiting their use in meeting varying product specifications caused by a change in patient’s medical condition or activity. To address this limitation, we design and optimize flexible single-bed MOC systems that are capable of meeting varying product specification requirements. Specifically, we employ a simulation-based optimization framework for optimizing flexible PSA- and pressure vacuum swing adsorption (PVSA)-based MOC systems. Detailed optimization studies are performed to benchmark the performance limits of LiX, LiLSX and 5A zeolite adsorbents. The results indicate that LiLSX outperforms both LiX and 5A, and can produce 90% pure oxygen at 21.7 L/min. Moreover, the LiLSX-based flexible PVSA system can manufacture varying levels of oxygen purity and flow rate in the range 93–95.7% and 1–15 L/min, respectively. The flexible MOC technology paves way for transitioning to an envisioned cyber-physical system with real-time oxygen demand sensing and delivery for improved patient care.Akhil AroraM. M. Faruque HasanNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Akhil Arora M. M. Faruque Hasan Flexible oxygen concentrators for medical applications
description	Abstract Medical oxygen concentrators (MOCs) are used for supplying medical grade oxygen to prevent hypoxemia-related complications related to COVID-19, chronic obstructive pulmonary disease (COPD), chronic bronchitis and pneumonia. MOCs often use a technology called pressure swing adsorption (PSA), which relies on nitrogen-selective adsorbents for producing oxygen from ambient air. MOCs are often designed for fixed product specifications, thereby limiting their use in meeting varying product specifications caused by a change in patient’s medical condition or activity. To address this limitation, we design and optimize flexible single-bed MOC systems that are capable of meeting varying product specification requirements. Specifically, we employ a simulation-based optimization framework for optimizing flexible PSA- and pressure vacuum swing adsorption (PVSA)-based MOC systems. Detailed optimization studies are performed to benchmark the performance limits of LiX, LiLSX and 5A zeolite adsorbents. The results indicate that LiLSX outperforms both LiX and 5A, and can produce 90% pure oxygen at 21.7 L/min. Moreover, the LiLSX-based flexible PVSA system can manufacture varying levels of oxygen purity and flow rate in the range 93–95.7% and 1–15 L/min, respectively. The flexible MOC technology paves way for transitioning to an envisioned cyber-physical system with real-time oxygen demand sensing and delivery for improved patient care.
format	article
author	Akhil Arora M. M. Faruque Hasan
author_facet	Akhil Arora M. M. Faruque Hasan
author_sort	Akhil Arora
title	Flexible oxygen concentrators for medical applications
title_short	Flexible oxygen concentrators for medical applications
title_full	Flexible oxygen concentrators for medical applications
title_fullStr	Flexible oxygen concentrators for medical applications
title_full_unstemmed	Flexible oxygen concentrators for medical applications
title_sort	flexible oxygen concentrators for medical applications
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d3d32e36961c4946b1a6e740b35fd3aa
work_keys_str_mv	AT akhilarora flexibleoxygenconcentratorsformedicalapplications AT mmfaruquehasan flexibleoxygenconcentratorsformedicalapplications
_version_	1718387172435820544

Flexible oxygen concentrators for medical applications

Ejemplares similares