The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium

Abstract. Kozhakhmetov S, Babenko D, Nurgaziyev M, Tuyakova A, Nurgozhina A, Muhanbetganov N, Chulenbayeva L, Sergazy S, Gulyayev A, Saliev T, Kushugulova A. 2020. The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium. Biodivers...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Samat Kozhakhmetov, DMITRIY BABENKO, MADIYAR NURGAZIYEV, ALTYNAY TUYAKOVA, AYAULYM NURGOZHINA, NURISLAM MUHANBETGANOV, LAURA CHULENBAYEVA, SHYNGGYS SERGAZY, ALEXANDR GULYAYEV, TIMUR SALIEV, ALMAGUL KUSHUGULOVA
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2020
Materias:	mmgpe dss-induced dysbiosis gut microbiome microbial diversity rats Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/d3d8788c8ce74feca376f9f26adbc87d
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d3d8788c8ce74feca376f9f26adbc87d
record_format	dspace
spelling	oai:doaj.org-article:d3d8788c8ce74feca376f9f26adbc87d2021-11-22T00:35:33ZThe combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium1412-033X2085-472210.13057/biodiv/d210558https://doaj.org/article/d3d8788c8ce74feca376f9f26adbc87d2020-04-01T00:00:00Zhttps://smujo.id/biodiv/article/view/5812https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Abstract. Kozhakhmetov S, Babenko D, Nurgaziyev M, Tuyakova A, Nurgozhina A, Muhanbetganov N, Chulenbayeva L, Sergazy S, Gulyayev A, Saliev T, Kushugulova A. 2020. The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium. Biodiversitas 21: 2275-2280. This study showed the potential of a biological product based on mare's milk and a complex of grape polyphenols to modulate intestinal microflora after dextran sulfate sodium (DSS)-induced dysbiosis. Rat ulcerative colitis has been developed using intra-gastric administration of 10% DSS solution. To track changes in the structure of the microbiome at all stages of the study, the next-generation sequencing of the 16S rRNA gene section and LotuS conveyor were used. The results of sequencing demonstrated a decrease in biological diversity of microbiota after the induction of colitis, and recovery after 7 days of use of the (MMGPE). The product induced the structural changes of the microbiome damaged by DSS. Representatives of SCFA producing bacteria increased concentrations of Prevotella, Alloprevotella, Lactobacillus, Ruminococcaceae, and Blautia.Samat KozhakhmetovDMITRIY BABENKOMADIYAR NURGAZIYEVALTYNAY TUYAKOVAAYAULYM NURGOZHINANURISLAM MUHANBETGANOVLAURA CHULENBAYEVASHYNGGYS SERGAZYALEXANDR GULYAYEVTIMUR SALIEVALMAGUL KUSHUGULOVAMBI & UNS Soloarticlemmgpedss-induced dysbiosisgut microbiomemicrobial diversityratsBiology (General)QH301-705.5ENBiodiversitas, Vol 21, Iss 5 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	mmgpe dss-induced dysbiosis gut microbiome microbial diversity rats Biology (General) QH301-705.5
spellingShingle	mmgpe dss-induced dysbiosis gut microbiome microbial diversity rats Biology (General) QH301-705.5 Samat Kozhakhmetov DMITRIY BABENKO MADIYAR NURGAZIYEV ALTYNAY TUYAKOVA AYAULYM NURGOZHINA NURISLAM MUHANBETGANOV LAURA CHULENBAYEVA SHYNGGYS SERGAZY ALEXANDR GULYAYEV TIMUR SALIEV ALMAGUL KUSHUGULOVA The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium
description	Abstract. Kozhakhmetov S, Babenko D, Nurgaziyev M, Tuyakova A, Nurgozhina A, Muhanbetganov N, Chulenbayeva L, Sergazy S, Gulyayev A, Saliev T, Kushugulova A. 2020. The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium. Biodiversitas 21: 2275-2280. This study showed the potential of a biological product based on mare's milk and a complex of grape polyphenols to modulate intestinal microflora after dextran sulfate sodium (DSS)-induced dysbiosis. Rat ulcerative colitis has been developed using intra-gastric administration of 10% DSS solution. To track changes in the structure of the microbiome at all stages of the study, the next-generation sequencing of the 16S rRNA gene section and LotuS conveyor were used. The results of sequencing demonstrated a decrease in biological diversity of microbiota after the induction of colitis, and recovery after 7 days of use of the (MMGPE). The product induced the structural changes of the microbiome damaged by DSS. Representatives of SCFA producing bacteria increased concentrations of Prevotella, Alloprevotella, Lactobacillus, Ruminococcaceae, and Blautia.
format	article
author	Samat Kozhakhmetov DMITRIY BABENKO MADIYAR NURGAZIYEV ALTYNAY TUYAKOVA AYAULYM NURGOZHINA NURISLAM MUHANBETGANOV LAURA CHULENBAYEVA SHYNGGYS SERGAZY ALEXANDR GULYAYEV TIMUR SALIEV ALMAGUL KUSHUGULOVA
author_facet	Samat Kozhakhmetov DMITRIY BABENKO MADIYAR NURGAZIYEV ALTYNAY TUYAKOVA AYAULYM NURGOZHINA NURISLAM MUHANBETGANOV LAURA CHULENBAYEVA SHYNGGYS SERGAZY ALEXANDR GULYAYEV TIMUR SALIEV ALMAGUL KUSHUGULOVA
author_sort	Samat Kozhakhmetov
title	The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium
title_short	The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium
title_full	The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium
title_fullStr	The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium
title_full_unstemmed	The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium
title_sort	combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium
publisher	MBI & UNS Solo
publishDate	2020
url	https://doaj.org/article/d3d8788c8ce74feca376f9f26adbc87d
work_keys_str_mv	AT samatkozhakhmetov thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT dmitriybabenko thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT madiyarnurgaziyev thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT altynaytuyakova thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT ayaulymnurgozhina thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT nurislammuhanbetganov thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT laurachulenbayeva thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT shynggyssergazy thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT alexandrgulyayev thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT timursaliev thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT almagulkushugulova thecombinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT samatkozhakhmetov combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT dmitriybabenko combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT madiyarnurgaziyev combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT altynaytuyakova combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT ayaulymnurgozhina combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT nurislammuhanbetganov combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT laurachulenbayeva combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT shynggyssergazy combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT alexandrgulyayev combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT timursaliev combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium AT almagulkushugulova combinationofmaresmilkandgrapepolyphenolextractfortreatmentofdysbiosisinducedbydextransulfatesodium
_version_	1718418551133437952

The combination of mare's milk and grape polyphenol extract for treatment of dysbiosis induced by dextran sulfate sodium

Ejemplares similares