BIOTRANSFORMATION OF THE COMPOUNDS 2-PHENYLETHANOL AND ACETOPHENONE BY THE PHYTOPHATOGEN FUNGUS <I>Botryodiplodia theobromae</I>

In this study, biotransformations of the substrates 2-phenilethanol 1 and acetophenone 2 achieve by the phylamentous phytopatogenic fungus Botryodiplodia theobromae, are evaluated; the process is carried out in liquid media culture Czapeck-Dox to an average temperature 24 ºC, relative humidity betwe...

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Autores principales:	Rodrigo VELASCO B., Iván D. VALVERDE P., Diego L. DURANGO R., Carlos M. GARCÍA P.
Formato:	article
Lenguaje:	EN
Publicado:	Universidad de Antioquia 2009
Materias:	Enzymatic hydroxylations enzymatic reduction of aromatic ketone enzymatic esterification Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
Acceso en línea:	https://doaj.org/article/d3dcacb2045443daa302ec4a3962a91f
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spelling	oai:doaj.org-article:d3dcacb2045443daa302ec4a3962a91f2021-11-19T04:21:05ZBIOTRANSFORMATION OF THE COMPOUNDS 2-PHENYLETHANOL AND ACETOPHENONE BY THE PHYTOPHATOGEN FUNGUS <I>Botryodiplodia theobromae</I>0121-40042145-2660https://doaj.org/article/d3dcacb2045443daa302ec4a3962a91f2009-02-01T00:00:00Zhttps://revistas.udea.edu.co/index.php/vitae/article/view/607https://doaj.org/toc/0121-4004https://doaj.org/toc/2145-2660In this study, biotransformations of the substrates 2-phenilethanol 1 and acetophenone 2 achieve by the phylamentous phytopatogenic fungus Botryodiplodia theobromae, are evaluated; the process is carried out in liquid media culture Czapeck-Dox to an average temperature 24 ºC, relative humidity between 45 % to 60 % and with agitation in shaker 150 rpm. The pathogen is obtained from infected commercial fruits of avocado, acquired at the centers of trade in the city of Medellín (Antioquia-Colombia) and it is characterized morphologically in the Phytopathology Laboratory of the University National Colombia, Medellín. The biotransformation of the substrate 1 produces the metabolites phenylethanodiol 3, 2- phenylacetic acid 4, phenylacetate 2-phenylethyl 5, acetate of 2-phenylethanol 6, and from substrate 2 are obtained the metabolites 1-phenylethanol 7, 2-phenilacetic acid 6, 2-phenylethanol 1, 2-phenylethanal 8, o-hydroxiacetophenone 9 and acetate of 1-phenylethanol 10. The structures of metabolic products are determined by gas chromatography coupled with mass spectrometry (GC-MS) and nuclear magnetic resonance of proton and carbon (1H and 13C NMR). The process is marked by tendency of the pathogen to produce hydroxylations on the alkylic chain and some on the aromatic chain. Additionally, it has the capability to reduce to the carbonyl group and produce esterification reaction in the hydroxyl groups. Rodrigo VELASCO B.Iván D. VALVERDE P.Diego L. DURANGO R.Carlos M. GARCÍA P.Universidad de AntioquiaarticleEnzymatic hydroxylationsenzymatic reduction of aromatic ketoneenzymatic esterificationFood processing and manufactureTP368-456Pharmaceutical industryHD9665-9675ENVitae, Vol 14, Iss 2 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Enzymatic hydroxylations enzymatic reduction of aromatic ketone enzymatic esterification Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675
spellingShingle	Enzymatic hydroxylations enzymatic reduction of aromatic ketone enzymatic esterification Food processing and manufacture TP368-456 Pharmaceutical industry HD9665-9675 Rodrigo VELASCO B. Iván D. VALVERDE P. Diego L. DURANGO R. Carlos M. GARCÍA P. BIOTRANSFORMATION OF THE COMPOUNDS 2-PHENYLETHANOL AND ACETOPHENONE BY THE PHYTOPHATOGEN FUNGUS <I>Botryodiplodia theobromae</I>
description	In this study, biotransformations of the substrates 2-phenilethanol 1 and acetophenone 2 achieve by the phylamentous phytopatogenic fungus Botryodiplodia theobromae, are evaluated; the process is carried out in liquid media culture Czapeck-Dox to an average temperature 24 ºC, relative humidity between 45 % to 60 % and with agitation in shaker 150 rpm. The pathogen is obtained from infected commercial fruits of avocado, acquired at the centers of trade in the city of Medellín (Antioquia-Colombia) and it is characterized morphologically in the Phytopathology Laboratory of the University National Colombia, Medellín. The biotransformation of the substrate 1 produces the metabolites phenylethanodiol 3, 2- phenylacetic acid 4, phenylacetate 2-phenylethyl 5, acetate of 2-phenylethanol 6, and from substrate 2 are obtained the metabolites 1-phenylethanol 7, 2-phenilacetic acid 6, 2-phenylethanol 1, 2-phenylethanal 8, o-hydroxiacetophenone 9 and acetate of 1-phenylethanol 10. The structures of metabolic products are determined by gas chromatography coupled with mass spectrometry (GC-MS) and nuclear magnetic resonance of proton and carbon (1H and 13C NMR). The process is marked by tendency of the pathogen to produce hydroxylations on the alkylic chain and some on the aromatic chain. Additionally, it has the capability to reduce to the carbonyl group and produce esterification reaction in the hydroxyl groups.
format	article
author	Rodrigo VELASCO B. Iván D. VALVERDE P. Diego L. DURANGO R. Carlos M. GARCÍA P.
author_facet	Rodrigo VELASCO B. Iván D. VALVERDE P. Diego L. DURANGO R. Carlos M. GARCÍA P.
author_sort	Rodrigo VELASCO B.
title	BIOTRANSFORMATION OF THE COMPOUNDS 2-PHENYLETHANOL AND ACETOPHENONE BY THE PHYTOPHATOGEN FUNGUS <I>Botryodiplodia theobromae</I>
title_short	BIOTRANSFORMATION OF THE COMPOUNDS 2-PHENYLETHANOL AND ACETOPHENONE BY THE PHYTOPHATOGEN FUNGUS <I>Botryodiplodia theobromae</I>
title_full	BIOTRANSFORMATION OF THE COMPOUNDS 2-PHENYLETHANOL AND ACETOPHENONE BY THE PHYTOPHATOGEN FUNGUS <I>Botryodiplodia theobromae</I>
title_fullStr	BIOTRANSFORMATION OF THE COMPOUNDS 2-PHENYLETHANOL AND ACETOPHENONE BY THE PHYTOPHATOGEN FUNGUS <I>Botryodiplodia theobromae</I>
title_full_unstemmed	BIOTRANSFORMATION OF THE COMPOUNDS 2-PHENYLETHANOL AND ACETOPHENONE BY THE PHYTOPHATOGEN FUNGUS <I>Botryodiplodia theobromae</I>
title_sort	biotransformation of the compounds 2-phenylethanol and acetophenone by the phytophatogen fungus <i>botryodiplodia theobromae</i>
publisher	Universidad de Antioquia
publishDate	2009
url	https://doaj.org/article/d3dcacb2045443daa302ec4a3962a91f
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BIOTRANSFORMATION OF THE COMPOUNDS 2-PHENYLETHANOL AND ACETOPHENONE BY THE PHYTOPHATOGEN FUNGUS <I>Botryodiplodia theobromae</I>

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