HIV viral load suppression following intensive adherence counseling among people living with HIV on treatment at military-managed health facilities in Uganda

Background: Uniformed service personnel have an increased risk of poor viral load suppression (VLS). This study was performed to evaluate the outcomes of interventions to improve VLS in the 28 military health facilities in Uganda.Methods: This operational research was conducted between October 2018...

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Autores principales:	Bernard Kikaire, Michael Ssemanda, Alex Asiimwe, Miriam Nakanwagi, Twaha Rwegyema, Gloria Seruwagi, Stephen Lawoko, Evarlyne Asiimwe, Cassette Wamundu, Ambrose Musinguzi, Eric Lugada, Elizabeth Turesson, Marni Laverentz, Denis Bwayo
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	HIV Viral load Intensive adherence counselling Military Low and middle-income countries Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/d3e15b116bfa49fc8227f10d238afdf3
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spelling	oai:doaj.org-article:d3e15b116bfa49fc8227f10d238afdf32021-11-30T04:14:01ZHIV viral load suppression following intensive adherence counseling among people living with HIV on treatment at military-managed health facilities in Uganda1201-971210.1016/j.ijid.2021.08.057https://doaj.org/article/d3e15b116bfa49fc8227f10d238afdf32021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1201971221006901https://doaj.org/toc/1201-9712Background: Uniformed service personnel have an increased risk of poor viral load suppression (VLS). This study was performed to evaluate the outcomes of interventions to improve VLS in the 28 military health facilities in Uganda.Methods: This operational research was conducted between October 2018 and September 2019, among people living with HIV (PLHIV) in the 28 health facilities managed by the military in Uganda. Patients with a viral load (VL) >1000 copies/ml received three sessions of intensive adherence counselling (IAC), 1 month apart, after which a repeat VL was done. The main outcome was the proportion with a suppressed VL following IAC.Results: Of the 965 participants included in this analysis, 592 (61.4%) were male and 367 (38.3%) were female. Average age was 35.5 ± 13.7 years, and 87.8% had at least one IAC session. At least 48.2% had a suppressed repeat VL. IAC increased the odds of VLS by 82% (P = 0.004), with adjusted OR of 1.56 (P = 0.054). An initial VL >10 000 copies/ml, being on antiretroviral therapy for at least 2 years, being male, and being <18 years of age were associated with repeat VL non-suppression.Conclusions: IAC marginally improved VL suppression. There is a need to improve IAC in military health facilities.Bernard KikaireMichael SsemandaAlex AsiimweMiriam NakanwagiTwaha RwegyemaGloria SeruwagiStephen LawokoEvarlyne AsiimweCassette WamunduAmbrose MusinguziEric LugadaElizabeth TuressonMarni LaverentzDenis BwayoElsevierarticleHIVViral loadIntensive adherence counsellingMilitaryLow and middle-income countriesInfectious and parasitic diseasesRC109-216ENInternational Journal of Infectious Diseases, Vol 112, Iss , Pp 45-51 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	HIV Viral load Intensive adherence counselling Military Low and middle-income countries Infectious and parasitic diseases RC109-216
spellingShingle	HIV Viral load Intensive adherence counselling Military Low and middle-income countries Infectious and parasitic diseases RC109-216 Bernard Kikaire Michael Ssemanda Alex Asiimwe Miriam Nakanwagi Twaha Rwegyema Gloria Seruwagi Stephen Lawoko Evarlyne Asiimwe Cassette Wamundu Ambrose Musinguzi Eric Lugada Elizabeth Turesson Marni Laverentz Denis Bwayo HIV viral load suppression following intensive adherence counseling among people living with HIV on treatment at military-managed health facilities in Uganda
description	Background: Uniformed service personnel have an increased risk of poor viral load suppression (VLS). This study was performed to evaluate the outcomes of interventions to improve VLS in the 28 military health facilities in Uganda.Methods: This operational research was conducted between October 2018 and September 2019, among people living with HIV (PLHIV) in the 28 health facilities managed by the military in Uganda. Patients with a viral load (VL) >1000 copies/ml received three sessions of intensive adherence counselling (IAC), 1 month apart, after which a repeat VL was done. The main outcome was the proportion with a suppressed VL following IAC.Results: Of the 965 participants included in this analysis, 592 (61.4%) were male and 367 (38.3%) were female. Average age was 35.5 ± 13.7 years, and 87.8% had at least one IAC session. At least 48.2% had a suppressed repeat VL. IAC increased the odds of VLS by 82% (P = 0.004), with adjusted OR of 1.56 (P = 0.054). An initial VL >10 000 copies/ml, being on antiretroviral therapy for at least 2 years, being male, and being <18 years of age were associated with repeat VL non-suppression.Conclusions: IAC marginally improved VL suppression. There is a need to improve IAC in military health facilities.
format	article
author	Bernard Kikaire Michael Ssemanda Alex Asiimwe Miriam Nakanwagi Twaha Rwegyema Gloria Seruwagi Stephen Lawoko Evarlyne Asiimwe Cassette Wamundu Ambrose Musinguzi Eric Lugada Elizabeth Turesson Marni Laverentz Denis Bwayo
author_facet	Bernard Kikaire Michael Ssemanda Alex Asiimwe Miriam Nakanwagi Twaha Rwegyema Gloria Seruwagi Stephen Lawoko Evarlyne Asiimwe Cassette Wamundu Ambrose Musinguzi Eric Lugada Elizabeth Turesson Marni Laverentz Denis Bwayo
author_sort	Bernard Kikaire
title	HIV viral load suppression following intensive adherence counseling among people living with HIV on treatment at military-managed health facilities in Uganda
title_short	HIV viral load suppression following intensive adherence counseling among people living with HIV on treatment at military-managed health facilities in Uganda
title_full	HIV viral load suppression following intensive adherence counseling among people living with HIV on treatment at military-managed health facilities in Uganda
title_fullStr	HIV viral load suppression following intensive adherence counseling among people living with HIV on treatment at military-managed health facilities in Uganda
title_full_unstemmed	HIV viral load suppression following intensive adherence counseling among people living with HIV on treatment at military-managed health facilities in Uganda
title_sort	hiv viral load suppression following intensive adherence counseling among people living with hiv on treatment at military-managed health facilities in uganda
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/d3e15b116bfa49fc8227f10d238afdf3
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HIV viral load suppression following intensive adherence counseling among people living with HIV on treatment at military-managed health facilities in Uganda

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