An updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013–2018

Abstract Introduction The most common cancers in the UK are keratinocyte cancers (KCs): the combined term for basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (cSCCs). Registration of KC is challenging due to high numbers and multiplicity of tumours per person. Methods We provide...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	M. Kwiatkowska, S. Ahmed, M. Ardern‐Jones, L. A. Bhatti, T. O. Bleiker, A. Gavin, S. Hussain, D. W. Huws, L. Irvine, S. M. Langan, G. W. M. Millington, H. Mitchell, R. Murphy, L. Paley, C. M. Proby, C. S. Thomson, R. Thomas, C. Turner, S. Vernon, Z. C. Venables
Formato:	article
Lenguaje:	EN
Publicado:	Wiley 2021
Materias:	Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/d3e1f4018ef244e59ad4feeb4f5dcf60
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d3e1f4018ef244e59ad4feeb4f5dcf60
record_format	dspace
spelling	oai:doaj.org-article:d3e1f4018ef244e59ad4feeb4f5dcf602021-12-02T11:13:08ZAn updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013–20182690-442X10.1002/ski2.61https://doaj.org/article/d3e1f4018ef244e59ad4feeb4f5dcf602021-12-01T00:00:00Zhttps://doi.org/10.1002/ski2.61https://doaj.org/toc/2690-442XAbstract Introduction The most common cancers in the UK are keratinocyte cancers (KCs): the combined term for basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (cSCCs). Registration of KC is challenging due to high numbers and multiplicity of tumours per person. Methods We provide an updated report on the descriptive epidemiology of trends in KC incidence for the resident populations of UK countries (England, Northern Ireland, Scotland and Wales) using population‐based cancer registry and pathology report data, 2013–18. Results Substantial increases in cSCC incidence in England, Scotland and Northern Ireland can be detected for the period of 2013–18, and the incidence of cSCC also increased in Wales from 2016 to 2018. In contrast, however, the pattern of annual change in the incidence of BCC across the nations differs. In England, the incidence of BCC declined slightly from 2016 to 2018, however, the overall trend across 2013–18 is not statistically significant. In Scotland, the incidence of BCC shows some variability, declining in 2017 before increasing in 2018, and the overall trend across 2013–18 was also not statistically significant. In Northern Ireland, the incidence of BCC increased significantly over the study period, and in Wales, the incidence of BCC increased from 2016 to 2018. One in five people will develop non‐melanoma skin cancers (NMSC) in their lifetime in England. This estimate is much higher than the lifetime risk of melanoma (1 in 36 males and 1 in 47 females born after 1960 in the UK), which further highlights the burden of the disease and importance of early prevention strategies. Conclusions We highlight how common these tumours are by publishing the first ever lifetime incidence of NMSC. Additionally, the first time reporting of the age standardised incidence of KC in Wales further confirms the scale of the disease burden posed by these cancers in the UK. With approximately one in five people developing NMSC in their lifetime, optimisation of skin cancer prevention, management and research are essential.M. KwiatkowskaS. AhmedM. Ardern‐JonesL. A. BhattiT. O. BleikerA. GavinS. HussainD. W. HuwsL. IrvineS. M. LanganG. W. M. MillingtonH. MitchellR. MurphyL. PaleyC. M. ProbyC. S. ThomsonR. ThomasC. TurnerS. VernonZ. C. VenablesWileyarticleDermatologyRL1-803ENSkin Health and Disease, Vol 1, Iss 4, Pp n/a-n/a (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Dermatology RL1-803
spellingShingle	Dermatology RL1-803 M. Kwiatkowska S. Ahmed M. Ardern‐Jones L. A. Bhatti T. O. Bleiker A. Gavin S. Hussain D. W. Huws L. Irvine S. M. Langan G. W. M. Millington H. Mitchell R. Murphy L. Paley C. M. Proby C. S. Thomson R. Thomas C. Turner S. Vernon Z. C. Venables An updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013–2018
description	Abstract Introduction The most common cancers in the UK are keratinocyte cancers (KCs): the combined term for basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (cSCCs). Registration of KC is challenging due to high numbers and multiplicity of tumours per person. Methods We provide an updated report on the descriptive epidemiology of trends in KC incidence for the resident populations of UK countries (England, Northern Ireland, Scotland and Wales) using population‐based cancer registry and pathology report data, 2013–18. Results Substantial increases in cSCC incidence in England, Scotland and Northern Ireland can be detected for the period of 2013–18, and the incidence of cSCC also increased in Wales from 2016 to 2018. In contrast, however, the pattern of annual change in the incidence of BCC across the nations differs. In England, the incidence of BCC declined slightly from 2016 to 2018, however, the overall trend across 2013–18 is not statistically significant. In Scotland, the incidence of BCC shows some variability, declining in 2017 before increasing in 2018, and the overall trend across 2013–18 was also not statistically significant. In Northern Ireland, the incidence of BCC increased significantly over the study period, and in Wales, the incidence of BCC increased from 2016 to 2018. One in five people will develop non‐melanoma skin cancers (NMSC) in their lifetime in England. This estimate is much higher than the lifetime risk of melanoma (1 in 36 males and 1 in 47 females born after 1960 in the UK), which further highlights the burden of the disease and importance of early prevention strategies. Conclusions We highlight how common these tumours are by publishing the first ever lifetime incidence of NMSC. Additionally, the first time reporting of the age standardised incidence of KC in Wales further confirms the scale of the disease burden posed by these cancers in the UK. With approximately one in five people developing NMSC in their lifetime, optimisation of skin cancer prevention, management and research are essential.
format	article
author	M. Kwiatkowska S. Ahmed M. Ardern‐Jones L. A. Bhatti T. O. Bleiker A. Gavin S. Hussain D. W. Huws L. Irvine S. M. Langan G. W. M. Millington H. Mitchell R. Murphy L. Paley C. M. Proby C. S. Thomson R. Thomas C. Turner S. Vernon Z. C. Venables
author_facet	M. Kwiatkowska S. Ahmed M. Ardern‐Jones L. A. Bhatti T. O. Bleiker A. Gavin S. Hussain D. W. Huws L. Irvine S. M. Langan G. W. M. Millington H. Mitchell R. Murphy L. Paley C. M. Proby C. S. Thomson R. Thomas C. Turner S. Vernon Z. C. Venables
author_sort	M. Kwiatkowska
title	An updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013–2018
title_short	An updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013–2018
title_full	An updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013–2018
title_fullStr	An updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013–2018
title_full_unstemmed	An updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013–2018
title_sort	updated report on the incidence and epidemiological trends of keratinocyte cancers in the united kingdom 2013–2018
publisher	Wiley
publishDate	2021
url	https://doaj.org/article/d3e1f4018ef244e59ad4feeb4f5dcf60
work_keys_str_mv	AT mkwiatkowska anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT sahmed anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT mardernjones anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT labhatti anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT tobleiker anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT agavin anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT shussain anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT dwhuws anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT lirvine anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT smlangan anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT gwmmillington anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT hmitchell anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT rmurphy anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT lpaley anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT cmproby anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT csthomson anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT rthomas anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT cturner anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT svernon anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT zcvenables anupdatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT mkwiatkowska updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT sahmed updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT mardernjones updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT labhatti updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT tobleiker updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT agavin updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT shussain updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT dwhuws updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT lirvine updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT smlangan updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT gwmmillington updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT hmitchell updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT rmurphy updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT lpaley updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT cmproby updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT csthomson updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT rthomas updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT cturner updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT svernon updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018 AT zcvenables updatedreportontheincidenceandepidemiologicaltrendsofkeratinocytecancersintheunitedkingdom20132018
_version_	1718396139910201344

An updated report on the incidence and epidemiological trends of keratinocyte cancers in the United Kingdom 2013–2018

Ejemplares similares