MRI-based identification of undifferentiated cells: looking at the two faces of Janus

Ciprian Tomuleasa,1,2 Ioan Stefan Florian,3 Cristian Berce,4 Alexandru Irimie,5,6 Ioana Berindan-Neagoe,2,7,9 Andrei Cucuianu1,8 1Department of Hematology, Ion Chiricuta Cancer Center, Cluj Napoca, Romania; 2Research Center for Functional Genomics and Translational Medicine, Iuliu Hatieganu Univers...

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Autores principales:	Tomuleasa C, Florian IS, Berce C, Irimie A, Berindan-Neagoe I, Cucuianu A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d3eb0d897a284d5cb42ea72f71ad18f1
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spelling	oai:doaj.org-article:d3eb0d897a284d5cb42ea72f71ad18f12021-12-02T02:46:36ZMRI-based identification of undifferentiated cells: looking at the two faces of Janus1178-2013https://doaj.org/article/d3eb0d897a284d5cb42ea72f71ad18f12014-02-01T00:00:00Zhttp://www.dovepress.com/variability-in-contrast-agent-uptake-by-different-but-similletter-a15771https://doaj.org/toc/1178-2013 Ciprian Tomuleasa,1,2 Ioan Stefan Florian,3 Cristian Berce,4 Alexandru Irimie,5,6 Ioana Berindan-Neagoe,2,7,9 Andrei Cucuianu1,8 1Department of Hematology, Ion Chiricuta Cancer Center, Cluj Napoca, Romania; 2Research Center for Functional Genomics and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 3Department of Neurosurgery, 4Animal Facility, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 5Department of Surgery, Ion Chiricuta Cancer Center, Cluj Napoca, Romania; 6Department of Oncology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 7Department of Functional Genomics, The Oncology Institute Ion Chiricuta, Cluj Napoca, Romania; 8Department of Hematology, 9Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, RomaniaWe have read with great interest the paper of Ketkar-Atre et al,1 in which they have developed a new way of tracking stem cells after transplantation using a magnetic resonance imaging (MRI)-based method. They have proven using high resolution electron microscopy that various types of undifferentiated cells, also known as stem cells, have a differentiation uptake of iron oxide nanoparticles according to their size and proliferation rate. Due to its super-paramagnetic properties, iron oxide is slowly finding its way from the laboratory to the clinic. When combined with MRI, it can very efficiently track a stem cell in vivo, as in the case of autologous transplantation,2,3 but also for other conditions such as Duchenne muscular dystrophy.View original paper by Ketkar-Atre et al.Tomuleasa CFlorian ISBerce CIrimie ABerindan-Neagoe ICucuianu ADove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 865-866 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Tomuleasa C Florian IS Berce C Irimie A Berindan-Neagoe I Cucuianu A MRI-based identification of undifferentiated cells: looking at the two faces of Janus
description	Ciprian Tomuleasa,1,2 Ioan Stefan Florian,3 Cristian Berce,4 Alexandru Irimie,5,6 Ioana Berindan-Neagoe,2,7,9 Andrei Cucuianu1,8 1Department of Hematology, Ion Chiricuta Cancer Center, Cluj Napoca, Romania; 2Research Center for Functional Genomics and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 3Department of Neurosurgery, 4Animal Facility, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 5Department of Surgery, Ion Chiricuta Cancer Center, Cluj Napoca, Romania; 6Department of Oncology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, Romania; 7Department of Functional Genomics, The Oncology Institute Ion Chiricuta, Cluj Napoca, Romania; 8Department of Hematology, 9Department of Immunology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj Napoca, RomaniaWe have read with great interest the paper of Ketkar-Atre et al,1 in which they have developed a new way of tracking stem cells after transplantation using a magnetic resonance imaging (MRI)-based method. They have proven using high resolution electron microscopy that various types of undifferentiated cells, also known as stem cells, have a differentiation uptake of iron oxide nanoparticles according to their size and proliferation rate. Due to its super-paramagnetic properties, iron oxide is slowly finding its way from the laboratory to the clinic. When combined with MRI, it can very efficiently track a stem cell in vivo, as in the case of autologous transplantation,2,3 but also for other conditions such as Duchenne muscular dystrophy.View original paper by Ketkar-Atre et al.
format	article
author	Tomuleasa C Florian IS Berce C Irimie A Berindan-Neagoe I Cucuianu A
author_facet	Tomuleasa C Florian IS Berce C Irimie A Berindan-Neagoe I Cucuianu A
author_sort	Tomuleasa C
title	MRI-based identification of undifferentiated cells: looking at the two faces of Janus
title_short	MRI-based identification of undifferentiated cells: looking at the two faces of Janus
title_full	MRI-based identification of undifferentiated cells: looking at the two faces of Janus
title_fullStr	MRI-based identification of undifferentiated cells: looking at the two faces of Janus
title_full_unstemmed	MRI-based identification of undifferentiated cells: looking at the two faces of Janus
title_sort	mri-based identification of undifferentiated cells: looking at the two faces of janus
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/d3eb0d897a284d5cb42ea72f71ad18f1
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MRI-based identification of undifferentiated cells: looking at the two faces of Janus

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