Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report

A 48-year-old Caucasian woman with history of multiple sclerosis (MS) presented with erythematous papulonodular lesions in her extremities and trunk. She was being treated with glatiramer acetate (GA) for the past 10 years and the glatiramoid, Glatopa, for 2 years prior to this presentation. A skin...

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Autores principales:	Afsaneh Shirani, Scott R Dalton, Eric J Avery, Lakshman Arcot Jayagopal, Christina Meyer, Olaf Stuve, Rana Zabad
Formato:	article
Lenguaje:	EN
Publicado:	SAGE Publishing 2021
Materias:	Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/d3fdd3766ec346f58a66ac08837762f7
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spelling	oai:doaj.org-article:d3fdd3766ec346f58a66ac08837762f72021-11-21T01:33:19ZLymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report1179-573510.1177/11795735211053784https://doaj.org/article/d3fdd3766ec346f58a66ac08837762f72021-11-01T00:00:00Zhttps://doi.org/10.1177/11795735211053784https://doaj.org/toc/1179-5735A 48-year-old Caucasian woman with history of multiple sclerosis (MS) presented with erythematous papulonodular lesions in her extremities and trunk. She was being treated with glatiramer acetate (GA) for the past 10 years and the glatiramoid, Glatopa, for 2 years prior to this presentation. A skin biopsy showed CD30 + lymphoproliferative disorder consistent with lymphomatoid papulosis (LyP). Three weeks after stopping Glatopa, her skin lesions were improved. It remains unclear whether GA’s or Glatopa’s capability to alter T-cell differentiation, may have a link with LyP. This case report is a reminder to be vigilant for skin lesions in patients with MS.Afsaneh ShiraniScott R DaltonEric J AveryLakshman Arcot JayagopalChristina MeyerOlaf StuveRana ZabadSAGE PublishingarticleNeurology. Diseases of the nervous systemRC346-429ENJournal of Central Nervous System Disease, Vol 13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurology. Diseases of the nervous system RC346-429 Afsaneh Shirani Scott R Dalton Eric J Avery Lakshman Arcot Jayagopal Christina Meyer Olaf Stuve Rana Zabad Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
description	A 48-year-old Caucasian woman with history of multiple sclerosis (MS) presented with erythematous papulonodular lesions in her extremities and trunk. She was being treated with glatiramer acetate (GA) for the past 10 years and the glatiramoid, Glatopa, for 2 years prior to this presentation. A skin biopsy showed CD30 + lymphoproliferative disorder consistent with lymphomatoid papulosis (LyP). Three weeks after stopping Glatopa, her skin lesions were improved. It remains unclear whether GA’s or Glatopa’s capability to alter T-cell differentiation, may have a link with LyP. This case report is a reminder to be vigilant for skin lesions in patients with MS.
format	article
author	Afsaneh Shirani Scott R Dalton Eric J Avery Lakshman Arcot Jayagopal Christina Meyer Olaf Stuve Rana Zabad
author_facet	Afsaneh Shirani Scott R Dalton Eric J Avery Lakshman Arcot Jayagopal Christina Meyer Olaf Stuve Rana Zabad
author_sort	Afsaneh Shirani
title	Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_short	Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_full	Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_fullStr	Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_full_unstemmed	Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report
title_sort	lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid glatopa for multiple sclerosis: a case report
publisher	SAGE Publishing
publishDate	2021
url	https://doaj.org/article/d3fdd3766ec346f58a66ac08837762f7
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Lymphomatoid papulosis in a patient treated with glatiramer acetate and the glatiramoid Glatopa for multiple sclerosis: A case report

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