Hypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks

Elad Shemesh,1 Barak Zafrir1,2 1Department of Cardiovascular Medicine, Lady Davis Carmel Medical Center, Haifa, Israel; 2Faculty of Medicine, Technion, Israel Institute of Medicine, Haifa, IsraelCorrespondence: Barak ZafrirDepartment of Cardiovascular Medicine, Lady Davis Carmel Medical Center, 7 Mi...

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Autores principales:	Shemesh E, Zafrir B
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2019
Materias:	Hypertriglyceridemia acute pancreatitis type 2 diabetes cardiovascular disease metabolic syndrome Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/d402fed05356432ab1be1375f6874416
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spelling	oai:doaj.org-article:d402fed05356432ab1be1375f68744162021-12-02T09:24:19ZHypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks1178-7007https://doaj.org/article/d402fed05356432ab1be1375f68744162019-10-01T00:00:00Zhttps://www.dovepress.com/hypertriglyceridemia-related-pancreatitis-in-patients-with-type-2-diab-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Elad Shemesh,1 Barak Zafrir1,2 1Department of Cardiovascular Medicine, Lady Davis Carmel Medical Center, Haifa, Israel; 2Faculty of Medicine, Technion, Israel Institute of Medicine, Haifa, IsraelCorrespondence: Barak ZafrirDepartment of Cardiovascular Medicine, Lady Davis Carmel Medical Center, 7 Michal Street, Haifa 3436212, IsraelTel +972-48250801Fax +972-48250916Email barakzmd@gmail.comAbstract: Disturbances in glucose and lipid homeostasis are cardinal features of the metabolic syndrome that affect millions of people worldwide. These conditions have multi-organ impact, and while cardiovascular effects are usually the core for studies and preventive measures, other systems may also be affected, including the pancreas. Acute pancreatitis related to severe hypertriglyceridemia is an under-recognized condition that could lead to significant morbidity and mortality. Therefore, when suspected, prompt diagnosis and treatment should be initiated to cover the various aspects of this disorder. Though commonly known to be associated with excess of alcohol use, hypertriglyceridemia-related pancreatitis is particularly observed in diabetics, especially when uncontrolled. Here, we portray the possible mechanisms and clinical features that link type 2 diabetes, hypertriglyceridemia and pancreatitis, and discuss their health-related outcomes and the current and novel treatment options for this unique disease.Keywords: hypertriglyceridemia, acute pancreatitis, type 2 diabetes, cardiovascular disease, metabolic syndromeShemesh EZafrir BDove Medical PressarticleHypertriglyceridemiaacute pancreatitistype 2 diabetescardiovascular diseasemetabolic syndromeSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 12, Pp 2041-2052 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Hypertriglyceridemia acute pancreatitis type 2 diabetes cardiovascular disease metabolic syndrome Specialties of internal medicine RC581-951
spellingShingle	Hypertriglyceridemia acute pancreatitis type 2 diabetes cardiovascular disease metabolic syndrome Specialties of internal medicine RC581-951 Shemesh E Zafrir B Hypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks
description	Elad Shemesh,1 Barak Zafrir1,2 1Department of Cardiovascular Medicine, Lady Davis Carmel Medical Center, Haifa, Israel; 2Faculty of Medicine, Technion, Israel Institute of Medicine, Haifa, IsraelCorrespondence: Barak ZafrirDepartment of Cardiovascular Medicine, Lady Davis Carmel Medical Center, 7 Michal Street, Haifa 3436212, IsraelTel +972-48250801Fax +972-48250916Email barakzmd@gmail.comAbstract: Disturbances in glucose and lipid homeostasis are cardinal features of the metabolic syndrome that affect millions of people worldwide. These conditions have multi-organ impact, and while cardiovascular effects are usually the core for studies and preventive measures, other systems may also be affected, including the pancreas. Acute pancreatitis related to severe hypertriglyceridemia is an under-recognized condition that could lead to significant morbidity and mortality. Therefore, when suspected, prompt diagnosis and treatment should be initiated to cover the various aspects of this disorder. Though commonly known to be associated with excess of alcohol use, hypertriglyceridemia-related pancreatitis is particularly observed in diabetics, especially when uncontrolled. Here, we portray the possible mechanisms and clinical features that link type 2 diabetes, hypertriglyceridemia and pancreatitis, and discuss their health-related outcomes and the current and novel treatment options for this unique disease.Keywords: hypertriglyceridemia, acute pancreatitis, type 2 diabetes, cardiovascular disease, metabolic syndrome
format	article
author	Shemesh E Zafrir B
author_facet	Shemesh E Zafrir B
author_sort	Shemesh E
title	Hypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks
title_short	Hypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks
title_full	Hypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks
title_fullStr	Hypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks
title_full_unstemmed	Hypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks
title_sort	hypertriglyceridemia-related pancreatitis in patients with type 2 diabetes: links and risks
publisher	Dove Medical Press
publishDate	2019
url	https://doaj.org/article/d402fed05356432ab1be1375f6874416
work_keys_str_mv	AT shemeshe hypertriglyceridemiarelatedpancreatitisinpatientswithtype2diabeteslinksandrisks AT zafrirb hypertriglyceridemiarelatedpancreatitisinpatientswithtype2diabeteslinksandrisks
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Hypertriglyceridemia-Related Pancreatitis In Patients With Type 2 Diabetes: Links And Risks

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