Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons

Reduction in food intake elicits neuroendocrine adaptations to counterregulate the negative energy balance, e.g. via reduction in leptin levels. Here, the authors identify an additional starvation signal, growth hormone (GH). Blocking GH receptor attenuates the fall of whole body energy expenditure...

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Autores principales:	Isadora C. Furigo, Pryscila D. S. Teixeira, Gabriel O. de Souza, Gisele C. L. Couto, Guadalupe García Romero, Mario Perelló, Renata Frazão, Lucila L. Elias, Martin Metzger, Edward O. List, John J. Kopchick, J. Donato
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d4067e42ca514c9c9b243f9101c626a6
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spelling	oai:doaj.org-article:d4067e42ca514c9c9b243f9101c626a62021-12-02T15:35:52ZGrowth hormone regulates neuroendocrine responses to weight loss via AgRP neurons10.1038/s41467-019-08607-12041-1723https://doaj.org/article/d4067e42ca514c9c9b243f9101c626a62019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08607-1https://doaj.org/toc/2041-1723Reduction in food intake elicits neuroendocrine adaptations to counterregulate the negative energy balance, e.g. via reduction in leptin levels. Here, the authors identify an additional starvation signal, growth hormone (GH). Blocking GH receptor attenuates the fall of whole body energy expenditure during food deprivation in mice.Isadora C. FurigoPryscila D. S. TeixeiraGabriel O. de SouzaGisele C. L. CoutoGuadalupe García RomeroMario PerellóRenata FrazãoLucila L. EliasMartin MetzgerEdward O. ListJohn J. KopchickJ. DonatoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Isadora C. Furigo Pryscila D. S. Teixeira Gabriel O. de Souza Gisele C. L. Couto Guadalupe García Romero Mario Perelló Renata Frazão Lucila L. Elias Martin Metzger Edward O. List John J. Kopchick J. Donato Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons
description	Reduction in food intake elicits neuroendocrine adaptations to counterregulate the negative energy balance, e.g. via reduction in leptin levels. Here, the authors identify an additional starvation signal, growth hormone (GH). Blocking GH receptor attenuates the fall of whole body energy expenditure during food deprivation in mice.
format	article
author	Isadora C. Furigo Pryscila D. S. Teixeira Gabriel O. de Souza Gisele C. L. Couto Guadalupe García Romero Mario Perelló Renata Frazão Lucila L. Elias Martin Metzger Edward O. List John J. Kopchick J. Donato
author_facet	Isadora C. Furigo Pryscila D. S. Teixeira Gabriel O. de Souza Gisele C. L. Couto Guadalupe García Romero Mario Perelló Renata Frazão Lucila L. Elias Martin Metzger Edward O. List John J. Kopchick J. Donato
author_sort	Isadora C. Furigo
title	Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons
title_short	Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons
title_full	Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons
title_fullStr	Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons
title_full_unstemmed	Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons
title_sort	growth hormone regulates neuroendocrine responses to weight loss via agrp neurons
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d4067e42ca514c9c9b243f9101c626a6
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Growth hormone regulates neuroendocrine responses to weight loss via AgRP neurons

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