In vitro and in vivo effects of insulin-producing cells generated by xeno-antigen free 3D culture with RCP piece

In vitro and in vivo effects of insulin-producing cells generated by xeno-antigen free 3D culture with RCP piece

Abstract To establish widespread cell therapy for type 1 diabetes mellitus, we aimed to develop an effective protocol for generating insulin-producing cells (IPCs) from adipose-derived stem cells (ADSCs). We established a 3D culture using a human recombinant peptide (RCP) petaloid μ-piece with xeno-...

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Bibliographic Details
Main Authors: Tetsuya Ikemoto, Rui Feng, Shu-ichi Iwahashi, Shinichiro Yamada, Yu Saito, Yuji Morine, Satoru Imura, Munehide Matsuhisa, Mitsuo Shimada
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/d40d9f4dd7634f25b2ef7f90de61850e
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