Parsimonious higher-order hidden Markov models for improved array-CGH analysis with applications to Arabidopsis thaliana.

Array-based comparative genomic hybridization (Array-CGH) is an important technology in molecular biology for the detection of DNA copy number polymorphisms between closely related genomes. Hidden Markov Models (HMMs) are popular tools for the analysis of Array-CGH data, but current methods are only...

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Autores principales: Michael Seifert, André Gohr, Marc Strickert, Ivo Grosse
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/d4228748ac3244cc99c7c36767d30014
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