Long-term effects of malnutrition on severity of COVID-19

Abstract The COVID-19 pandemic is a public health crisis that has the potential to exacerbate worldwide malnutrition. This study examines whether patients with a history of malnutrition are predisposed to severe COVID-19. To do so, data on 103,099 COVID-19 inpatient encounters from 56 hospitals in t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Alec Kurtz, Kenneth Grant, Rachel Marano, Antonio Arrieta, William Feaster, Caroline Steele, Louis Ehwerhemuepha
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d42c0cbee56c4b90898013ab6a206eb6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d42c0cbee56c4b90898013ab6a206eb6
record_format	dspace
spelling	oai:doaj.org-article:d42c0cbee56c4b90898013ab6a206eb62021-12-02T16:17:18ZLong-term effects of malnutrition on severity of COVID-1910.1038/s41598-021-94138-z2045-2322https://doaj.org/article/d42c0cbee56c4b90898013ab6a206eb62021-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-94138-zhttps://doaj.org/toc/2045-2322Abstract The COVID-19 pandemic is a public health crisis that has the potential to exacerbate worldwide malnutrition. This study examines whether patients with a history of malnutrition are predisposed to severe COVID-19. To do so, data on 103,099 COVID-19 inpatient encounters from 56 hospitals in the United States between March 2020 and June 2020 were retrieved from the Cerner COVID-19 Dataset. Patients with a history of malnutrition between 2015 and 2019 were identified, and a random intercept logistic regression models for pediatric and adult patients were built controlling for patient demographics, socioeconomic status, admission vital signs, and related comorbidities. Statistical interactions between malnutrition and patient age were significant in both the pediatric [log-odds and 95% confidence interval: 0.094 (0.012, 0.175)] and adult [− 0.014 (− 0.021, − 0.006] models. These interactions, together with the main effect terms of malnutrition and age, imply higher odds for severe COVID-19 for children between 6 and 17 years with history of malnutrition. Even higher odds of severe COVID-19 exist for adults (with history of malnutrition) between 18 and 79 years. These results indicate that the long-term effect of malnutrition predisposes patients to severe COVID-19 in an age-dependent way.Alec KurtzKenneth GrantRachel MaranoAntonio ArrietaKenneth GrantWilliam FeasterCaroline SteeleLouis EhwerhemuephaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Alec Kurtz Kenneth Grant Rachel Marano Antonio Arrieta Kenneth Grant William Feaster Caroline Steele Louis Ehwerhemuepha Long-term effects of malnutrition on severity of COVID-19
description	Abstract The COVID-19 pandemic is a public health crisis that has the potential to exacerbate worldwide malnutrition. This study examines whether patients with a history of malnutrition are predisposed to severe COVID-19. To do so, data on 103,099 COVID-19 inpatient encounters from 56 hospitals in the United States between March 2020 and June 2020 were retrieved from the Cerner COVID-19 Dataset. Patients with a history of malnutrition between 2015 and 2019 were identified, and a random intercept logistic regression models for pediatric and adult patients were built controlling for patient demographics, socioeconomic status, admission vital signs, and related comorbidities. Statistical interactions between malnutrition and patient age were significant in both the pediatric [log-odds and 95% confidence interval: 0.094 (0.012, 0.175)] and adult [− 0.014 (− 0.021, − 0.006] models. These interactions, together with the main effect terms of malnutrition and age, imply higher odds for severe COVID-19 for children between 6 and 17 years with history of malnutrition. Even higher odds of severe COVID-19 exist for adults (with history of malnutrition) between 18 and 79 years. These results indicate that the long-term effect of malnutrition predisposes patients to severe COVID-19 in an age-dependent way.
format	article
author	Alec Kurtz Kenneth Grant Rachel Marano Antonio Arrieta Kenneth Grant William Feaster Caroline Steele Louis Ehwerhemuepha
author_facet	Alec Kurtz Kenneth Grant Rachel Marano Antonio Arrieta Kenneth Grant William Feaster Caroline Steele Louis Ehwerhemuepha
author_sort	Alec Kurtz
title	Long-term effects of malnutrition on severity of COVID-19
title_short	Long-term effects of malnutrition on severity of COVID-19
title_full	Long-term effects of malnutrition on severity of COVID-19
title_fullStr	Long-term effects of malnutrition on severity of COVID-19
title_full_unstemmed	Long-term effects of malnutrition on severity of COVID-19
title_sort	long-term effects of malnutrition on severity of covid-19
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d42c0cbee56c4b90898013ab6a206eb6
work_keys_str_mv	AT aleckurtz longtermeffectsofmalnutritiononseverityofcovid19 AT kennethgrant longtermeffectsofmalnutritiononseverityofcovid19 AT rachelmarano longtermeffectsofmalnutritiononseverityofcovid19 AT antonioarrieta longtermeffectsofmalnutritiononseverityofcovid19 AT kennethgrant longtermeffectsofmalnutritiononseverityofcovid19 AT williamfeaster longtermeffectsofmalnutritiononseverityofcovid19 AT carolinesteele longtermeffectsofmalnutritiononseverityofcovid19 AT louisehwerhemuepha longtermeffectsofmalnutritiononseverityofcovid19
_version_	1718384257709113344

Long-term effects of malnutrition on severity of COVID-19

Ejemplares similares