A multiscale signalling network map of innate immune response in cancer reveals cell heterogeneity signatures

The complexity of the innate immune response to cancer makes interpretation of large data sets challenging. Here, the authors provide an integrated multi-scale map of signalling networks representing the different immune cells and their interactions and show its utility for data interpretation.

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Detalles Bibliográficos
Autores principales: Maria Kondratova, Urszula Czerwinska, Nicolas Sompairac, Sebastian D. Amigorena, Vassili Soumelis, Emmanuel Barillot, Andrei Zinovyev, Inna Kuperstein
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d431490a7031492db83471392f547ffe
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Sumario:The complexity of the innate immune response to cancer makes interpretation of large data sets challenging. Here, the authors provide an integrated multi-scale map of signalling networks representing the different immune cells and their interactions and show its utility for data interpretation.