Neurotrophin receptor tyrosine kinases regulated with near-infrared light

Optical control over receptor tyrosine kinase (RTK) activity can find application in both basic biology and synthetic biology. Here the authors combine the photosensory module of DrBphP bacterial phytochrome with the Trk family of RTKs to obtain Trks that are reversibly switchable with near-infrared...

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Autores principales: Anna V. Leopold, Konstantin G. Chernov, Anton A. Shemetov, Vladislav V. Verkhusha
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d447bf17660142128b2c06f41c792119
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spelling oai:doaj.org-article:d447bf17660142128b2c06f41c7921192021-12-02T14:39:39ZNeurotrophin receptor tyrosine kinases regulated with near-infrared light10.1038/s41467-019-08988-32041-1723https://doaj.org/article/d447bf17660142128b2c06f41c7921192019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08988-3https://doaj.org/toc/2041-1723Optical control over receptor tyrosine kinase (RTK) activity can find application in both basic biology and synthetic biology. Here the authors combine the photosensory module of DrBphP bacterial phytochrome with the Trk family of RTKs to obtain Trks that are reversibly switchable with near-infrared and far-red light.Anna V. LeopoldKonstantin G. ChernovAnton A. ShemetovVladislav V. VerkhushaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anna V. Leopold
Konstantin G. Chernov
Anton A. Shemetov
Vladislav V. Verkhusha
Neurotrophin receptor tyrosine kinases regulated with near-infrared light
description Optical control over receptor tyrosine kinase (RTK) activity can find application in both basic biology and synthetic biology. Here the authors combine the photosensory module of DrBphP bacterial phytochrome with the Trk family of RTKs to obtain Trks that are reversibly switchable with near-infrared and far-red light.
format article
author Anna V. Leopold
Konstantin G. Chernov
Anton A. Shemetov
Vladislav V. Verkhusha
author_facet Anna V. Leopold
Konstantin G. Chernov
Anton A. Shemetov
Vladislav V. Verkhusha
author_sort Anna V. Leopold
title Neurotrophin receptor tyrosine kinases regulated with near-infrared light
title_short Neurotrophin receptor tyrosine kinases regulated with near-infrared light
title_full Neurotrophin receptor tyrosine kinases regulated with near-infrared light
title_fullStr Neurotrophin receptor tyrosine kinases regulated with near-infrared light
title_full_unstemmed Neurotrophin receptor tyrosine kinases regulated with near-infrared light
title_sort neurotrophin receptor tyrosine kinases regulated with near-infrared light
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d447bf17660142128b2c06f41c792119
work_keys_str_mv AT annavleopold neurotrophinreceptortyrosinekinasesregulatedwithnearinfraredlight
AT konstantingchernov neurotrophinreceptortyrosinekinasesregulatedwithnearinfraredlight
AT antonashemetov neurotrophinreceptortyrosinekinasesregulatedwithnearinfraredlight
AT vladislavvverkhusha neurotrophinreceptortyrosinekinasesregulatedwithnearinfraredlight
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