Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages

Shape transformation of proteins created by design in the laboratory is challenging. Here, the authors present a disulfide-mediated approach for the preparation of 16-mer, 24-mer, and 48-mer nanocages from an 8-mer bowl-like protein building block.

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Autores principales: Jiachen Zang, Hai Chen, Xiaorong Zhang, Chenxi Zhang, Jing Guo, Ming Du, Guanghua Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d4496bef09364daa81f5f10a6ef0d7ac
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spelling oai:doaj.org-article:d4496bef09364daa81f5f10a6ef0d7ac2021-12-02T17:01:28ZDisulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages10.1038/s41467-019-08788-92041-1723https://doaj.org/article/d4496bef09364daa81f5f10a6ef0d7ac2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08788-9https://doaj.org/toc/2041-1723Shape transformation of proteins created by design in the laboratory is challenging. Here, the authors present a disulfide-mediated approach for the preparation of 16-mer, 24-mer, and 48-mer nanocages from an 8-mer bowl-like protein building block.Jiachen ZangHai ChenXiaorong ZhangChenxi ZhangJing GuoMing DuGuanghua ZhaoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jiachen Zang
Hai Chen
Xiaorong Zhang
Chenxi Zhang
Jing Guo
Ming Du
Guanghua Zhao
Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages
description Shape transformation of proteins created by design in the laboratory is challenging. Here, the authors present a disulfide-mediated approach for the preparation of 16-mer, 24-mer, and 48-mer nanocages from an 8-mer bowl-like protein building block.
format article
author Jiachen Zang
Hai Chen
Xiaorong Zhang
Chenxi Zhang
Jing Guo
Ming Du
Guanghua Zhao
author_facet Jiachen Zang
Hai Chen
Xiaorong Zhang
Chenxi Zhang
Jing Guo
Ming Du
Guanghua Zhao
author_sort Jiachen Zang
title Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages
title_short Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages
title_full Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages
title_fullStr Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages
title_full_unstemmed Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages
title_sort disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d4496bef09364daa81f5f10a6ef0d7ac
work_keys_str_mv AT jiachenzang disulfidemediatedconversionof8merbowllikeproteinarchitectureintothreedifferentnanocages
AT haichen disulfidemediatedconversionof8merbowllikeproteinarchitectureintothreedifferentnanocages
AT xiaorongzhang disulfidemediatedconversionof8merbowllikeproteinarchitectureintothreedifferentnanocages
AT chenxizhang disulfidemediatedconversionof8merbowllikeproteinarchitectureintothreedifferentnanocages
AT jingguo disulfidemediatedconversionof8merbowllikeproteinarchitectureintothreedifferentnanocages
AT mingdu disulfidemediatedconversionof8merbowllikeproteinarchitectureintothreedifferentnanocages
AT guanghuazhao disulfidemediatedconversionof8merbowllikeproteinarchitectureintothreedifferentnanocages
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