Analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss

Background: Sudden sensorineural hearing loss (SSHL) refers to the sudden occurrence of unexplained sensorineural hearing loss. The present study showed that different systemic diseases had different influence on the occurrence and hearing outcome of SSHL. Thyroid hormone is one of the important fac...

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Autores principales:	Yuhua Zhu, Dan Bing, Dayong Wang, Lidong Zhao, Zifang Yin, Qiujing Zhang, Jing Guan, Qiuju Wang
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2021
Materias:	Thyroid dysfunction Sudden sensorineural hearing loss Hearing outcome Otorhinolaryngology RF1-547 Surgery RD1-811
Acceso en línea:	https://doaj.org/article/d44c6d522e884d3da6279bd62b70d49d
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spelling	oai:doaj.org-article:d44c6d522e884d3da6279bd62b70d49d2021-12-02T18:11:44ZAnalysis of thyroid dysfunction in patients with sudden sensorineural hearing loss2095-881110.1016/j.wjorl.2019.02.002https://doaj.org/article/d44c6d522e884d3da6279bd62b70d49d2021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095881119301003https://doaj.org/toc/2095-8811Background: Sudden sensorineural hearing loss (SSHL) refers to the sudden occurrence of unexplained sensorineural hearing loss. The present study showed that different systemic diseases had different influence on the occurrence and hearing outcome of SSHL. Thyroid hormone is one of the important factors for the development of fetal ear and auditory function. However, the distribution of thyroid dysfunction in SSHL patients and the effect of thyroid dysfunction on the occurrence and hearing outcome of SSHL has not been studied. Methods: In this study, a retrospective analysis had been done in 676 patients with SSHL. We had described the distribution of thyroid function in patients with SSHL in detail, and by the statistical method, analyzed the relationship between the hearing outcome and thyroid dysfunction, respectively. Results: In all patients, 24.41% (165/676) had abnormal thyroid function testing results. The onset age of SSHL in FT3 abnormal group (including low and high group) was younger than that in normal FT3 group. Recovery group had more patients with lower-than-normal T3 level as compared to non-recovery patients. Significant associations between T3 levels and hearing outcome were observed in the subgroup with longer time elapse between symptom onset and treatment (≥14 d). Conclusion: The incidence of thyroid dysfunction in SSHL is significantly higher than in the general population. There was obvious relationship between T3 and FT3 item of thyroid dysfunction and the onset time and hearing outcome of SSHL, which indicated that T3 or FT3 indicator may be one of the affecting factors for the SSHL. Early screening and diagnosis of thyroid dysfunction, especial T3 level, may help to evaluate the prognosis in SSHL patients.Yuhua ZhuDan BingDayong WangLidong ZhaoZifang YinQiujing ZhangJing GuanQiuju WangKeAi Communications Co., Ltd.articleThyroid dysfunctionSudden sensorineural hearing lossHearing outcomeOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 7, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Thyroid dysfunction Sudden sensorineural hearing loss Hearing outcome Otorhinolaryngology RF1-547 Surgery RD1-811
spellingShingle	Thyroid dysfunction Sudden sensorineural hearing loss Hearing outcome Otorhinolaryngology RF1-547 Surgery RD1-811 Yuhua Zhu Dan Bing Dayong Wang Lidong Zhao Zifang Yin Qiujing Zhang Jing Guan Qiuju Wang Analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss
description	Background: Sudden sensorineural hearing loss (SSHL) refers to the sudden occurrence of unexplained sensorineural hearing loss. The present study showed that different systemic diseases had different influence on the occurrence and hearing outcome of SSHL. Thyroid hormone is one of the important factors for the development of fetal ear and auditory function. However, the distribution of thyroid dysfunction in SSHL patients and the effect of thyroid dysfunction on the occurrence and hearing outcome of SSHL has not been studied. Methods: In this study, a retrospective analysis had been done in 676 patients with SSHL. We had described the distribution of thyroid function in patients with SSHL in detail, and by the statistical method, analyzed the relationship between the hearing outcome and thyroid dysfunction, respectively. Results: In all patients, 24.41% (165/676) had abnormal thyroid function testing results. The onset age of SSHL in FT3 abnormal group (including low and high group) was younger than that in normal FT3 group. Recovery group had more patients with lower-than-normal T3 level as compared to non-recovery patients. Significant associations between T3 levels and hearing outcome were observed in the subgroup with longer time elapse between symptom onset and treatment (≥14 d). Conclusion: The incidence of thyroid dysfunction in SSHL is significantly higher than in the general population. There was obvious relationship between T3 and FT3 item of thyroid dysfunction and the onset time and hearing outcome of SSHL, which indicated that T3 or FT3 indicator may be one of the affecting factors for the SSHL. Early screening and diagnosis of thyroid dysfunction, especial T3 level, may help to evaluate the prognosis in SSHL patients.
format	article
author	Yuhua Zhu Dan Bing Dayong Wang Lidong Zhao Zifang Yin Qiujing Zhang Jing Guan Qiuju Wang
author_facet	Yuhua Zhu Dan Bing Dayong Wang Lidong Zhao Zifang Yin Qiujing Zhang Jing Guan Qiuju Wang
author_sort	Yuhua Zhu
title	Analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss
title_short	Analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss
title_full	Analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss
title_fullStr	Analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss
title_full_unstemmed	Analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss
title_sort	analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss
publisher	KeAi Communications Co., Ltd.
publishDate	2021
url	https://doaj.org/article/d44c6d522e884d3da6279bd62b70d49d
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_version_	1718378600064876544

Analysis of thyroid dysfunction in patients with sudden sensorineural hearing loss

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