Treatment of adult ADHD: Is current knowledge useful to clinicians?

Terje Torgersen1,2, Bj&oslash;rn Gjervan1,3, Kirsten Rasmussen31Department of Psychiatry, Sykehuset Levanger, Helse Nord-Troendelag HF, Levanger, Norway; 2Faculty of Medicine and 3Department of Psychology, Norwegian University of Science and Technology, Trondheim, NorwayAbstract: Psychostimu...

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Autores principales:	Terje Torgersen, Bj&oslash;rn Gjervan, Kirsten Rasmussen
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/d457312db5d2440582bad32329b0fd1f
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spelling	oai:doaj.org-article:d457312db5d2440582bad32329b0fd1f2021-12-02T08:44:57ZTreatment of adult ADHD: Is current knowledge useful to clinicians?1176-63281178-2021https://doaj.org/article/d457312db5d2440582bad32329b0fd1f2008-03-01T00:00:00Zhttp://www.dovepress.com/treatment-of-adult-adhd-is-current-knowledge-useful-to-clinicians-a984https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Terje Torgersen1,2, Bj&oslash;rn Gjervan1,3, Kirsten Rasmussen31Department of Psychiatry, Sykehuset Levanger, Helse Nord-Troendelag HF, Levanger, Norway; 2Faculty of Medicine and 3Department of Psychology, Norwegian University of Science and Technology, Trondheim, NorwayAbstract: Psychostimulant drugs have for decades been considered the cornerstone of ADHD treatment. Non-stimulant drugs have also been reported successful. However, many controlled studies exclude patients with comorbidities typical for patients seen in clinical setting. Many patients are also considered non-responders to medication. Current knowledge might not be directly useful to clinicians. The present article reviews the literature on pharmacological and psychotherapeutic treatment in adult ADHD emphasizing comorbidity and other clinically important factors, as well as ADHD specific outcomes. Thirty-three relevant studies of pharmacotherapy and three studies of psychotherapy were included. Most subjects had little current comorbidity, but some studies included subjects with substance use disorder. Significant effect of treatment on ADHD symptoms was found in most studies using pharmacotherapy and all studies of psychotherapy. Both positive and negative effects on comorbid anxiety and depression measures were reported. Pharmacotherapy did not seem to have effect on substance use disorder. Few pharmacotherapy studies conducted any long-term follow-up; two studies that did, found that most subjects had discontinued medication. A clear-cut dose-respons relationship was not substanciated. In conclusion, clinicians have good support for both pharmacological and psychotherapeutic treatment of ADHD in adults, but should take additional measures to deal with comorbidities as well as treatment adherence.Keywords: ADHD, adults, treatment, stimulants, psychotherapy, comorbidity Terje TorgersenBj&oslash;rn GjervanKirsten RasmussenDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 1, Pp 177-186 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Terje Torgersen Bj&oslash;rn Gjervan Kirsten Rasmussen Treatment of adult ADHD: Is current knowledge useful to clinicians?
description	Terje Torgersen1,2, Bj&oslash;rn Gjervan1,3, Kirsten Rasmussen31Department of Psychiatry, Sykehuset Levanger, Helse Nord-Troendelag HF, Levanger, Norway; 2Faculty of Medicine and 3Department of Psychology, Norwegian University of Science and Technology, Trondheim, NorwayAbstract: Psychostimulant drugs have for decades been considered the cornerstone of ADHD treatment. Non-stimulant drugs have also been reported successful. However, many controlled studies exclude patients with comorbidities typical for patients seen in clinical setting. Many patients are also considered non-responders to medication. Current knowledge might not be directly useful to clinicians. The present article reviews the literature on pharmacological and psychotherapeutic treatment in adult ADHD emphasizing comorbidity and other clinically important factors, as well as ADHD specific outcomes. Thirty-three relevant studies of pharmacotherapy and three studies of psychotherapy were included. Most subjects had little current comorbidity, but some studies included subjects with substance use disorder. Significant effect of treatment on ADHD symptoms was found in most studies using pharmacotherapy and all studies of psychotherapy. Both positive and negative effects on comorbid anxiety and depression measures were reported. Pharmacotherapy did not seem to have effect on substance use disorder. Few pharmacotherapy studies conducted any long-term follow-up; two studies that did, found that most subjects had discontinued medication. A clear-cut dose-respons relationship was not substanciated. In conclusion, clinicians have good support for both pharmacological and psychotherapeutic treatment of ADHD in adults, but should take additional measures to deal with comorbidities as well as treatment adherence.Keywords: ADHD, adults, treatment, stimulants, psychotherapy, comorbidity
format	article
author	Terje Torgersen Bj&oslash;rn Gjervan Kirsten Rasmussen
author_facet	Terje Torgersen Bj&oslash;rn Gjervan Kirsten Rasmussen
author_sort	Terje Torgersen
title	Treatment of adult ADHD: Is current knowledge useful to clinicians?
title_short	Treatment of adult ADHD: Is current knowledge useful to clinicians?
title_full	Treatment of adult ADHD: Is current knowledge useful to clinicians?
title_fullStr	Treatment of adult ADHD: Is current knowledge useful to clinicians?
title_full_unstemmed	Treatment of adult ADHD: Is current knowledge useful to clinicians?
title_sort	treatment of adult adhd: is current knowledge useful to clinicians?
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/d457312db5d2440582bad32329b0fd1f
work_keys_str_mv	AT terjetorgersen treatmentofadultadhdiscurrentknowledgeusefultoclinicians AT bjamposlashrngjervan treatmentofadultadhdiscurrentknowledgeusefultoclinicians AT kirstenrasmussen treatmentofadultadhdiscurrentknowledgeusefultoclinicians
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Treatment of adult ADHD: Is current knowledge useful to clinicians?

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