SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion
Sustained Wnt secretion requires the endosomal SNX3-retromer complex for endosome-to-trans-Golgi network transport of the internalised Wnt chaperone Wntless. Here the authors show that in both C. elegans and human cells, SNX3-retromer requires an evolutionary conserved membrane remodelling complex f...
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Autores principales: | Ian J. McGough, Reinoud E. A. de Groot, Adam P. Jellett, Marco C. Betist, Katherine C. Varandas, Chris M. Danson, Kate J. Heesom, Hendrik C. Korswagen, Peter J. Cullen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/d470221d33d847238609773f477f4c71 |
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