Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis

Beige and brown fat may influence systemic metabolism through secreted signals. Here the authors identify a panel of metabolites secreted from beige and brown fat cells, which signal to influence fat tissue and skeletal muscle metabolism and have anti-obesity effects in mouse models of obesity and d...

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Autores principales:	Anna Whitehead, Fynn N. Krause, Amy Moran, Amanda D. V. MacCannell, Jason L. Scragg, Ben D. McNally, Edward Boateng, Steven A. Murfitt, Samuel Virtue, John Wright, Jack Garnham, Graeme R. Davies, James Dodgson, Jurgen E. Schneider, Andrew J. Murray, Christopher Church, Antonio Vidal-Puig, Klaus K. Witte, Julian L. Griffin, Lee D. Roberts
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d473c1c97b044c2fb72f34ce9316e47f
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spelling	oai:doaj.org-article:d473c1c97b044c2fb72f34ce9316e47f2021-12-02T17:04:01ZBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis10.1038/s41467-021-22272-32041-1723https://doaj.org/article/d473c1c97b044c2fb72f34ce9316e47f2021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22272-3https://doaj.org/toc/2041-1723Beige and brown fat may influence systemic metabolism through secreted signals. Here the authors identify a panel of metabolites secreted from beige and brown fat cells, which signal to influence fat tissue and skeletal muscle metabolism and have anti-obesity effects in mouse models of obesity and diabetes.Anna WhiteheadFynn N. KrauseAmy MoranAmanda D. V. MacCannellJason L. ScraggBen D. McNallyEdward BoatengSteven A. MurfittSamuel VirtueJohn WrightJack GarnhamGraeme R. DaviesJames DodgsonJurgen E. SchneiderAndrew J. MurrayChristopher ChurchAntonio Vidal-PuigKlaus K. WitteJulian L. GriffinLee D. RobertsNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anna Whitehead Fynn N. Krause Amy Moran Amanda D. V. MacCannell Jason L. Scragg Ben D. McNally Edward Boateng Steven A. Murfitt Samuel Virtue John Wright Jack Garnham Graeme R. Davies James Dodgson Jurgen E. Schneider Andrew J. Murray Christopher Church Antonio Vidal-Puig Klaus K. Witte Julian L. Griffin Lee D. Roberts Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
description	Beige and brown fat may influence systemic metabolism through secreted signals. Here the authors identify a panel of metabolites secreted from beige and brown fat cells, which signal to influence fat tissue and skeletal muscle metabolism and have anti-obesity effects in mouse models of obesity and diabetes.
format	article
author	Anna Whitehead Fynn N. Krause Amy Moran Amanda D. V. MacCannell Jason L. Scragg Ben D. McNally Edward Boateng Steven A. Murfitt Samuel Virtue John Wright Jack Garnham Graeme R. Davies James Dodgson Jurgen E. Schneider Andrew J. Murray Christopher Church Antonio Vidal-Puig Klaus K. Witte Julian L. Griffin Lee D. Roberts
author_facet	Anna Whitehead Fynn N. Krause Amy Moran Amanda D. V. MacCannell Jason L. Scragg Ben D. McNally Edward Boateng Steven A. Murfitt Samuel Virtue John Wright Jack Garnham Graeme R. Davies James Dodgson Jurgen E. Schneider Andrew J. Murray Christopher Church Antonio Vidal-Puig Klaus K. Witte Julian L. Griffin Lee D. Roberts
author_sort	Anna Whitehead
title	Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
title_short	Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
title_full	Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
title_fullStr	Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
title_full_unstemmed	Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
title_sort	brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d473c1c97b044c2fb72f34ce9316e47f
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Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis

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