Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs
Several highly efficacious vaccines for SARS-CoV-2 have been developed and are used in the population. However, the current production capacity cannot meet the global demand. Therefore, additional vaccines—especially ones that can be produced locally and at low cost—are urgently needed. This work d...
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American Society for Microbiology
2021
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oai:doaj.org-article:d47ce303ae344529b5dda46a5d3fc7572021-11-03T21:52:35ZSafety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs2150-751110.1128/mBio.01908-21https://doaj.org/article/d47ce303ae344529b5dda46a5d3fc7572021-10-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mBio.01908-21https://doaj.org/toc/2150-7511 Several highly efficacious vaccines for SARS-CoV-2 have been developed and are used in the population. However, the current production capacity cannot meet the global demand. Therefore, additional vaccines—especially ones that can be produced locally and at low cost—are urgently needed. This work describes preclinical testing of a SARS-CoV-2 vaccine candidate which meets these criteria.Jesús Horacio Lara-PuenteJuan Manuel CarreñoWeina SunAlejandro Suárez-MartínezLuis Ramírez-MartínezFrancisco Quezada-MonroyGeorgina Paz-De la RosaRosalía Vigueras-MorenoGagandeep SinghOscar Rojas-MartínezHéctor Elías Chagoya-CortésDavid Sarfati-MizrahiErnesto Soto-PrianteConstantino López-MacíasFlorian KrammerFelipa Castro-PeraltaPeter PaleseAdolfo García-SastreBernardo Lozano-DubernardAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmBio, Vol 12, Iss 5 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Microbiology QR1-502 |
| spellingShingle |
Microbiology QR1-502 Jesús Horacio Lara-Puente Juan Manuel Carreño Weina Sun Alejandro Suárez-Martínez Luis Ramírez-Martínez Francisco Quezada-Monroy Georgina Paz-De la Rosa Rosalía Vigueras-Moreno Gagandeep Singh Oscar Rojas-Martínez Héctor Elías Chagoya-Cortés David Sarfati-Mizrahi Ernesto Soto-Priante Constantino López-Macías Florian Krammer Felipa Castro-Peralta Peter Palese Adolfo García-Sastre Bernardo Lozano-Dubernard Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs |
| description |
Several highly efficacious vaccines for SARS-CoV-2 have been developed and are used in the population. However, the current production capacity cannot meet the global demand. Therefore, additional vaccines—especially ones that can be produced locally and at low cost—are urgently needed. This work describes preclinical testing of a SARS-CoV-2 vaccine candidate which meets these criteria. |
| format |
article |
| author |
Jesús Horacio Lara-Puente Juan Manuel Carreño Weina Sun Alejandro Suárez-Martínez Luis Ramírez-Martínez Francisco Quezada-Monroy Georgina Paz-De la Rosa Rosalía Vigueras-Moreno Gagandeep Singh Oscar Rojas-Martínez Héctor Elías Chagoya-Cortés David Sarfati-Mizrahi Ernesto Soto-Priante Constantino López-Macías Florian Krammer Felipa Castro-Peralta Peter Palese Adolfo García-Sastre Bernardo Lozano-Dubernard |
| author_facet |
Jesús Horacio Lara-Puente Juan Manuel Carreño Weina Sun Alejandro Suárez-Martínez Luis Ramírez-Martínez Francisco Quezada-Monroy Georgina Paz-De la Rosa Rosalía Vigueras-Moreno Gagandeep Singh Oscar Rojas-Martínez Héctor Elías Chagoya-Cortés David Sarfati-Mizrahi Ernesto Soto-Priante Constantino López-Macías Florian Krammer Felipa Castro-Peralta Peter Palese Adolfo García-Sastre Bernardo Lozano-Dubernard |
| author_sort |
Jesús Horacio Lara-Puente |
| title |
Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs |
| title_short |
Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs |
| title_full |
Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs |
| title_fullStr |
Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs |
| title_full_unstemmed |
Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs |
| title_sort |
safety and immunogenicity of a newcastle disease virus vector-based sars-cov-2 vaccine candidate, avx/covid-12-hexapro (patria), in pigs |
| publisher |
American Society for Microbiology |
| publishDate |
2021 |
| url |
https://doaj.org/article/d47ce303ae344529b5dda46a5d3fc757 |
| work_keys_str_mv |
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