Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex
Many genes have oscillating gene expression pattern in circadian centers of the brain. This study shows cortical diurnal DNA methylation oscillation in a mouse model of Prader-Willi syndrome, and describes corresponding changes in gene expression and chromatin compaction.
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Nature Portfolio
2018
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oai:doaj.org-article:d481882ef53445478adf7400b2b40b3f2021-12-02T14:39:45ZSnord116-dependent diurnal rhythm of DNA methylation in mouse cortex10.1038/s41467-018-03676-02041-1723https://doaj.org/article/d481882ef53445478adf7400b2b40b3f2018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03676-0https://doaj.org/toc/2041-1723Many genes have oscillating gene expression pattern in circadian centers of the brain. This study shows cortical diurnal DNA methylation oscillation in a mouse model of Prader-Willi syndrome, and describes corresponding changes in gene expression and chromatin compaction.Rochelle L. CoulsonDag H. YasuiKeith W. DunawayBenjamin I. LauferAnnie Vogel CierniaYihui ZhuCharles E. MordauntTheresa S. TotahJanine M. LaSalleNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Rochelle L. Coulson Dag H. Yasui Keith W. Dunaway Benjamin I. Laufer Annie Vogel Ciernia Yihui Zhu Charles E. Mordaunt Theresa S. Totah Janine M. LaSalle Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex |
description |
Many genes have oscillating gene expression pattern in circadian centers of the brain. This study shows cortical diurnal DNA methylation oscillation in a mouse model of Prader-Willi syndrome, and describes corresponding changes in gene expression and chromatin compaction. |
format |
article |
author |
Rochelle L. Coulson Dag H. Yasui Keith W. Dunaway Benjamin I. Laufer Annie Vogel Ciernia Yihui Zhu Charles E. Mordaunt Theresa S. Totah Janine M. LaSalle |
author_facet |
Rochelle L. Coulson Dag H. Yasui Keith W. Dunaway Benjamin I. Laufer Annie Vogel Ciernia Yihui Zhu Charles E. Mordaunt Theresa S. Totah Janine M. LaSalle |
author_sort |
Rochelle L. Coulson |
title |
Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex |
title_short |
Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex |
title_full |
Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex |
title_fullStr |
Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex |
title_full_unstemmed |
Snord116-dependent diurnal rhythm of DNA methylation in mouse cortex |
title_sort |
snord116-dependent diurnal rhythm of dna methylation in mouse cortex |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/d481882ef53445478adf7400b2b40b3f |
work_keys_str_mv |
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1718390561805697024 |