Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores

During metaphase, k-fibre microtubules exert force on kinetochores, but there are also non-kinetochore microtubules close to kinetochores without a known function. Here the authors show that these microtubules, which they call bridging fibres, balance interkinetochore tension by bridging sister k-fi...

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Autores principales: Janko Kajtez, Anastasia Solomatina, Maja Novak, Bruno Polak, Kruno Vukušić, Jonas Rüdiger, Gheorghe Cojoc, Ana Milas, Ivana Šumanovac Šestak, Patrik Risteski, Federica Tavano, Anna H. Klemm, Emanuele Roscioli, Julie Welburn, Daniela Cimini, Matko Glunčić, Nenad Pavin, Iva M. Tolić
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Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/d4a8786484cf46a7a667bff22a510f7a
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spelling oai:doaj.org-article:d4a8786484cf46a7a667bff22a510f7a2021-12-02T15:33:48ZOverlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores10.1038/ncomms102982041-1723https://doaj.org/article/d4a8786484cf46a7a667bff22a510f7a2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10298https://doaj.org/toc/2041-1723During metaphase, k-fibre microtubules exert force on kinetochores, but there are also non-kinetochore microtubules close to kinetochores without a known function. Here the authors show that these microtubules, which they call bridging fibres, balance interkinetochore tension by bridging sister k-fibres.Janko KajtezAnastasia SolomatinaMaja NovakBruno PolakKruno VukušićJonas RüdigerGheorghe CojocAna MilasIvana Šumanovac ŠestakPatrik RisteskiFederica TavanoAnna H. KlemmEmanuele RoscioliJulie WelburnDaniela CiminiMatko GlunčićNenad PavinIva M. TolićNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Janko Kajtez
Anastasia Solomatina
Maja Novak
Bruno Polak
Kruno Vukušić
Jonas Rüdiger
Gheorghe Cojoc
Ana Milas
Ivana Šumanovac Šestak
Patrik Risteski
Federica Tavano
Anna H. Klemm
Emanuele Roscioli
Julie Welburn
Daniela Cimini
Matko Glunčić
Nenad Pavin
Iva M. Tolić
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
description During metaphase, k-fibre microtubules exert force on kinetochores, but there are also non-kinetochore microtubules close to kinetochores without a known function. Here the authors show that these microtubules, which they call bridging fibres, balance interkinetochore tension by bridging sister k-fibres.
format article
author Janko Kajtez
Anastasia Solomatina
Maja Novak
Bruno Polak
Kruno Vukušić
Jonas Rüdiger
Gheorghe Cojoc
Ana Milas
Ivana Šumanovac Šestak
Patrik Risteski
Federica Tavano
Anna H. Klemm
Emanuele Roscioli
Julie Welburn
Daniela Cimini
Matko Glunčić
Nenad Pavin
Iva M. Tolić
author_facet Janko Kajtez
Anastasia Solomatina
Maja Novak
Bruno Polak
Kruno Vukušić
Jonas Rüdiger
Gheorghe Cojoc
Ana Milas
Ivana Šumanovac Šestak
Patrik Risteski
Federica Tavano
Anna H. Klemm
Emanuele Roscioli
Julie Welburn
Daniela Cimini
Matko Glunčić
Nenad Pavin
Iva M. Tolić
author_sort Janko Kajtez
title Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
title_short Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
title_full Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
title_fullStr Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
title_full_unstemmed Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
title_sort overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/d4a8786484cf46a7a667bff22a510f7a
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