Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma
Chimeric antigen receptor (CAR)-based therapy for the treatment of liver cancer represents a promising therapeutic strategy. Here the authors show that CD147-targeting CAR-NK or CAR-T can induce anti-tumor activity against hepatocellular carcinoma in vitro and in vivo.
Enregistré dans:
| Auteurs principaux: | Hsiang-chi Tseng, Wei Xiong, Saiaditya Badeti, Yan Yang, Minh Ma, Ting Liu, Carlos A. Ramos, Gianpietro Dotti, Luke Fritzky, Jie-gen Jiang, Qing Yi, James Guarrera, Wei-Xing Zong, Chen Liu, Dongfang Liu |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/d4aefc73f7c342c4befc39c05ef9b986 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Chimeric antigen receptor modified T-cells for cancer treatment
par: Xiao Han, et autres
Publié: (2018) -
A TCR-based Chimeric Antigen Receptor
par: Even Walseng, et autres
Publié: (2017) -
Hepatitis E virus capsid as a carrier of exogenous antigens for the development of chimeric virus-like particles
par: Tianyu Lu, et autres
Publié: (2021) -
Acta No. 147
par: Banco Central de Chile
Publié: (2019) -
Structure-based design of chimeric antigens for multivalent protein vaccines
par: S. Hollingshead, et autres
Publié: (2018)