A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity

High or multiple doses of macrolide antibiotics, when given early in life, can perturb the metabolic and immunological development of lab mice. Here, Ruiz et al. show that even a single macrolide course, given early in life, leads to long-lasting changes in the gut microbiota and immune system of mi...

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Autores principales:	Victoria E. Ruiz, Thomas Battaglia, Zachary D. Kurtz, Luc Bijnens, Amy Ou, Isak Engstrand, Xuhui Zheng, Tadasu Iizumi, Briana J. Mullins, Christian L. Müller, Ken Cadwell, Richard Bonneau, Guillermo I. Perez-Perez, Martin J. Blaser
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d4b11426675d407594f768ad99b19727
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spelling	oai:doaj.org-article:d4b11426675d407594f768ad99b197272021-12-02T14:40:57ZA single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity10.1038/s41467-017-00531-62041-1723https://doaj.org/article/d4b11426675d407594f768ad99b197272017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00531-6https://doaj.org/toc/2041-1723High or multiple doses of macrolide antibiotics, when given early in life, can perturb the metabolic and immunological development of lab mice. Here, Ruiz et al. show that even a single macrolide course, given early in life, leads to long-lasting changes in the gut microbiota and immune system of mice.Victoria E. RuizThomas BattagliaZachary D. KurtzLuc BijnensAmy OuIsak EngstrandXuhui ZhengTadasu IizumiBriana J. MullinsChristian L. MüllerKen CadwellRichard BonneauGuillermo I. Perez-PerezMartin J. BlaserNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Victoria E. Ruiz Thomas Battaglia Zachary D. Kurtz Luc Bijnens Amy Ou Isak Engstrand Xuhui Zheng Tadasu Iizumi Briana J. Mullins Christian L. Müller Ken Cadwell Richard Bonneau Guillermo I. Perez-Perez Martin J. Blaser A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity
description	High or multiple doses of macrolide antibiotics, when given early in life, can perturb the metabolic and immunological development of lab mice. Here, Ruiz et al. show that even a single macrolide course, given early in life, leads to long-lasting changes in the gut microbiota and immune system of mice.
format	article
author	Victoria E. Ruiz Thomas Battaglia Zachary D. Kurtz Luc Bijnens Amy Ou Isak Engstrand Xuhui Zheng Tadasu Iizumi Briana J. Mullins Christian L. Müller Ken Cadwell Richard Bonneau Guillermo I. Perez-Perez Martin J. Blaser
author_facet	Victoria E. Ruiz Thomas Battaglia Zachary D. Kurtz Luc Bijnens Amy Ou Isak Engstrand Xuhui Zheng Tadasu Iizumi Briana J. Mullins Christian L. Müller Ken Cadwell Richard Bonneau Guillermo I. Perez-Perez Martin J. Blaser
author_sort	Victoria E. Ruiz
title	A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity
title_short	A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity
title_full	A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity
title_fullStr	A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity
title_full_unstemmed	A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity
title_sort	single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/d4b11426675d407594f768ad99b19727
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A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity

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