Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis

Allylic C–H activation of enol silyl ethers via one-electron oxidation is usually accompanied by undesired desilylation. Here, under hybrid photoredox and Brønsted base catalysis, the authors show the mild functionalization of enol silyl ethers, providing a platform to access an array of complex car...

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Autores principales:	Kohsuke Ohmatsu, Tsubasa Nakashima, Makoto Sato, Takashi Ooi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d4b34167696a4514b3e6b9637c57d34e
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spelling	oai:doaj.org-article:d4b34167696a4514b3e6b9637c57d34e2021-12-02T14:38:46ZDirect allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis10.1038/s41467-019-10641-y2041-1723https://doaj.org/article/d4b34167696a4514b3e6b9637c57d34e2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10641-yhttps://doaj.org/toc/2041-1723Allylic C–H activation of enol silyl ethers via one-electron oxidation is usually accompanied by undesired desilylation. Here, under hybrid photoredox and Brønsted base catalysis, the authors show the mild functionalization of enol silyl ethers, providing a platform to access an array of complex carbonyl compounds.Kohsuke OhmatsuTsubasa NakashimaMakoto SatoTakashi OoiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kohsuke Ohmatsu Tsubasa Nakashima Makoto Sato Takashi Ooi Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis
description	Allylic C–H activation of enol silyl ethers via one-electron oxidation is usually accompanied by undesired desilylation. Here, under hybrid photoredox and Brønsted base catalysis, the authors show the mild functionalization of enol silyl ethers, providing a platform to access an array of complex carbonyl compounds.
format	article
author	Kohsuke Ohmatsu Tsubasa Nakashima Makoto Sato Takashi Ooi
author_facet	Kohsuke Ohmatsu Tsubasa Nakashima Makoto Sato Takashi Ooi
author_sort	Kohsuke Ohmatsu
title	Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis
title_short	Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis
title_full	Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis
title_fullStr	Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis
title_full_unstemmed	Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis
title_sort	direct allylic c–h alkylation of enol silyl ethers enabled by photoredox–brønsted base hybrid catalysis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d4b34167696a4514b3e6b9637c57d34e
work_keys_str_mv	AT kohsukeohmatsu directallylicchalkylationofenolsilylethersenabledbyphotoredoxbrønstedbasehybridcatalysis AT tsubasanakashima directallylicchalkylationofenolsilylethersenabledbyphotoredoxbrønstedbasehybridcatalysis AT makotosato directallylicchalkylationofenolsilylethersenabledbyphotoredoxbrønstedbasehybridcatalysis AT takashiooi directallylicchalkylationofenolsilylethersenabledbyphotoredoxbrønstedbasehybridcatalysis
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Direct allylic C–H alkylation of enol silyl ethers enabled by photoredox–Brønsted base hybrid catalysis

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