Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance

Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance

Chronic stress is a risk factor for mood disorders, yet the molecular and circuit mechanisms of stress-induced changes are not well understood. Here, the authors report the role of the transcription factor ΔFosB in driving activity changes in response to stress in glutamatergic neurons in the ventra...

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Autores principales: Andrew L. Eagle, Claire E. Manning, Elizabeth S. Williams, Ryan M. Bastle, Paula A. Gajewski, Amber Garrison, Alexis J. Wirtz, Seda Akguen, Katie Brandel-Ankrapp, Wilson Endege, Frederick M. Boyce, Yoshinori N. Ohnishi, Michelle Mazei-Robison, Ian Maze, Rachel L. Neve, Alfred J. Robison
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/d4b95067e74845b094227a1938275611
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