Impact of sociodemographic factors on cognitive function in school-aged HIV-infected Nigerian children

Gbemisola O Boyede,1,2 Foluso EA Lesi,2 Veronica C Ezeaka,2 Charles S Umeh3 1Division of Developmental Paediatrics, School of Child and Adolescent Health, Red Cross War Memorial Children’s Hospital, University of Cape Town, Cape Town, South Africa; 2Department of Paediatrics, 3Clinical Psy...

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Autores principales:	Boyede GO, Lesi FEA, Ezeaka VC, Umeh CS
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/d4c59ec0b1834a79a5da05179ba26079
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spelling	oai:doaj.org-article:d4c59ec0b1834a79a5da05179ba260792021-12-02T01:18:56ZImpact of sociodemographic factors on cognitive function in school-aged HIV-infected Nigerian children1179-1373https://doaj.org/article/d4c59ec0b1834a79a5da05179ba260792013-07-01T00:00:00Zhttp://www.dovepress.com/impact-of-sociodemographic-factors-on-cognitive-function-in-school-age-a13662https://doaj.org/toc/1179-1373Gbemisola O Boyede,1,2 Foluso EA Lesi,2 Veronica C Ezeaka,2 Charles S Umeh3 1Division of Developmental Paediatrics, School of Child and Adolescent Health, Red Cross War Memorial Children’s Hospital, University of Cape Town, Cape Town, South Africa; 2Department of Paediatrics, 3Clinical Psychology Unit, Department of Psychiatry, Lagos University Teaching Hospital, Lagos, Nigeria Background: In this study, we sought to evaluate the influence of sociodemographic factors, ie, age, sex, socioeconomic status, maternal education, and human immunodeficiency virus (HIV) status, on cognitive performance in school-aged HIV-infected Nigerian children. Methods: Sixty-nine HIV-positive children aged 6–15 years were matched with 69 HIV-negative control children for age and sex. The children were subdivided for the purpose of analysis into two cognitive developmental stages using Piaget’s staging, ie, the concrete operational stage (6–11 years) and the formal operational stage (12–15 years). All participants underwent cognitive assessment using Raven’s Standard Progressive Matrices (RPM). Sociodemographic data for the study participants, ie, age, sex, socioeconomic status, and level of maternal education, were obtained using a study proforma. Logistic regression analyses were used to determine associations of HIV status and sociodemographic characteristics with RPM cognitive scores. Results: The overall mean RPM score for the HIV-positive children was 18.2 ± 9.8 (range 8.0–47.0) which was significantly lower than the score of 27.2 ± 13.8 (range 8.0–52.0) for the HIV-negative children (P < 0.001). On RPM grading, 56.5% of the HIV-positive children had cognitive performance at below average to intellectually defective range. Below average RPM scores were found to be significantly associated with younger age (6–11 years), positive HIV status, lower socioeconomic status, and low level of maternal education. Conclusion: Younger age, poor socioeconomic status, and low level of maternal education were factors apart from HIV infection that were significantly associated with low cognitive function in school-aged HIV-infected Nigerian children. Keywords: pediatric human immunodeficiency virus, cognitive assessment, school-aged children, Raven’s Progressive Matrices, NigeriaBoyede GOLesi FEAEzeaka VCUmeh CSDove Medical PressarticleImmunologic diseases. AllergyRC581-607ENHIV/AIDS: Research and Palliative Care, Vol 2013, Iss default, Pp 145-152 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Immunologic diseases. Allergy RC581-607
spellingShingle	Immunologic diseases. Allergy RC581-607 Boyede GO Lesi FEA Ezeaka VC Umeh CS Impact of sociodemographic factors on cognitive function in school-aged HIV-infected Nigerian children
description	Gbemisola O Boyede,1,2 Foluso EA Lesi,2 Veronica C Ezeaka,2 Charles S Umeh3 1Division of Developmental Paediatrics, School of Child and Adolescent Health, Red Cross War Memorial Children’s Hospital, University of Cape Town, Cape Town, South Africa; 2Department of Paediatrics, 3Clinical Psychology Unit, Department of Psychiatry, Lagos University Teaching Hospital, Lagos, Nigeria Background: In this study, we sought to evaluate the influence of sociodemographic factors, ie, age, sex, socioeconomic status, maternal education, and human immunodeficiency virus (HIV) status, on cognitive performance in school-aged HIV-infected Nigerian children. Methods: Sixty-nine HIV-positive children aged 6–15 years were matched with 69 HIV-negative control children for age and sex. The children were subdivided for the purpose of analysis into two cognitive developmental stages using Piaget’s staging, ie, the concrete operational stage (6–11 years) and the formal operational stage (12–15 years). All participants underwent cognitive assessment using Raven’s Standard Progressive Matrices (RPM). Sociodemographic data for the study participants, ie, age, sex, socioeconomic status, and level of maternal education, were obtained using a study proforma. Logistic regression analyses were used to determine associations of HIV status and sociodemographic characteristics with RPM cognitive scores. Results: The overall mean RPM score for the HIV-positive children was 18.2 ± 9.8 (range 8.0–47.0) which was significantly lower than the score of 27.2 ± 13.8 (range 8.0–52.0) for the HIV-negative children (P < 0.001). On RPM grading, 56.5% of the HIV-positive children had cognitive performance at below average to intellectually defective range. Below average RPM scores were found to be significantly associated with younger age (6–11 years), positive HIV status, lower socioeconomic status, and low level of maternal education. Conclusion: Younger age, poor socioeconomic status, and low level of maternal education were factors apart from HIV infection that were significantly associated with low cognitive function in school-aged HIV-infected Nigerian children. Keywords: pediatric human immunodeficiency virus, cognitive assessment, school-aged children, Raven’s Progressive Matrices, Nigeria
format	article
author	Boyede GO Lesi FEA Ezeaka VC Umeh CS
author_facet	Boyede GO Lesi FEA Ezeaka VC Umeh CS
author_sort	Boyede GO
title	Impact of sociodemographic factors on cognitive function in school-aged HIV-infected Nigerian children
title_short	Impact of sociodemographic factors on cognitive function in school-aged HIV-infected Nigerian children
title_full	Impact of sociodemographic factors on cognitive function in school-aged HIV-infected Nigerian children
title_fullStr	Impact of sociodemographic factors on cognitive function in school-aged HIV-infected Nigerian children
title_full_unstemmed	Impact of sociodemographic factors on cognitive function in school-aged HIV-infected Nigerian children
title_sort	impact of sociodemographic factors on cognitive function in school-aged hiv-infected nigerian children
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/d4c59ec0b1834a79a5da05179ba26079
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Impact of sociodemographic factors on cognitive function in school-aged HIV-infected Nigerian children

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