Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum

Striatal dopaminoceptive neurons are molecularly and functionally heterogeneous. Here, the authors provide the translatome of D2R striatal neurons and identified hundreds of region specific molecular markers as well as testing their resource to shed light into function.

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Autores principales: Emma Puighermanal, Laia Castell, Anna Esteve-Codina, Su Melser, Konstantin Kaganovsky, Charleine Zussy, Jihane Boubaker-Vitre, Marta Gut, Stephanie Rialle, Christoph Kellendonk, Elisenda Sanz, Albert Quintana, Giovanni Marsicano, Miquel Martin, Marcelo Rubinstein, Jean-Antoine Girault, Jun B. Ding, Emmanuel Valjent
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d4d48f37c7d94541a98488897d3e9b83
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spelling oai:doaj.org-article:d4d48f37c7d94541a98488897d3e9b832021-12-02T14:41:27ZFunctional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum10.1038/s41467-020-15716-92041-1723https://doaj.org/article/d4d48f37c7d94541a98488897d3e9b832020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15716-9https://doaj.org/toc/2041-1723Striatal dopaminoceptive neurons are molecularly and functionally heterogeneous. Here, the authors provide the translatome of D2R striatal neurons and identified hundreds of region specific molecular markers as well as testing their resource to shed light into function.Emma PuighermanalLaia CastellAnna Esteve-CodinaSu MelserKonstantin KaganovskyCharleine ZussyJihane Boubaker-VitreMarta GutStephanie RialleChristoph KellendonkElisenda SanzAlbert QuintanaGiovanni MarsicanoMiquel MartinMarcelo RubinsteinJean-Antoine GiraultJun B. DingEmmanuel ValjentNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Emma Puighermanal
Laia Castell
Anna Esteve-Codina
Su Melser
Konstantin Kaganovsky
Charleine Zussy
Jihane Boubaker-Vitre
Marta Gut
Stephanie Rialle
Christoph Kellendonk
Elisenda Sanz
Albert Quintana
Giovanni Marsicano
Miquel Martin
Marcelo Rubinstein
Jean-Antoine Girault
Jun B. Ding
Emmanuel Valjent
Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
description Striatal dopaminoceptive neurons are molecularly and functionally heterogeneous. Here, the authors provide the translatome of D2R striatal neurons and identified hundreds of region specific molecular markers as well as testing their resource to shed light into function.
format article
author Emma Puighermanal
Laia Castell
Anna Esteve-Codina
Su Melser
Konstantin Kaganovsky
Charleine Zussy
Jihane Boubaker-Vitre
Marta Gut
Stephanie Rialle
Christoph Kellendonk
Elisenda Sanz
Albert Quintana
Giovanni Marsicano
Miquel Martin
Marcelo Rubinstein
Jean-Antoine Girault
Jun B. Ding
Emmanuel Valjent
author_facet Emma Puighermanal
Laia Castell
Anna Esteve-Codina
Su Melser
Konstantin Kaganovsky
Charleine Zussy
Jihane Boubaker-Vitre
Marta Gut
Stephanie Rialle
Christoph Kellendonk
Elisenda Sanz
Albert Quintana
Giovanni Marsicano
Miquel Martin
Marcelo Rubinstein
Jean-Antoine Girault
Jun B. Ding
Emmanuel Valjent
author_sort Emma Puighermanal
title Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
title_short Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
title_full Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
title_fullStr Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
title_full_unstemmed Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
title_sort functional and molecular heterogeneity of d2r neurons along dorsal ventral axis in the striatum
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/d4d48f37c7d94541a98488897d3e9b83
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