Polycystic ovary syndrome - 80 years of research and new directions in the study (literature review)

The article presents the current data of history of polycystic ovary syndrome (PCOS) study. It contains studies of genetic susceptibility of PCOS, PCOS symptoms and connection with development of anxiety and depressive disorders. The article covers ethnic differences in the phenotypic manifestations...

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Autores principales:	L. V. Damdinova, O. Ya. Leshchenko
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	pcos stein-leventhal syndrome infertility oligomenorrhea insulin resistance hyperandrogenism hirsutism polycystic ovaries intestinal microbiota Science Q
Acceso en línea:	https://doaj.org/article/d4e5f80a771848219d499de1aa3117a9
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spelling	oai:doaj.org-article:d4e5f80a771848219d499de1aa3117a92021-11-23T06:14:35ZPolycystic ovary syndrome - 80 years of research and new directions in the study (literature review)2541-94202587-959610.12737/23421https://doaj.org/article/d4e5f80a771848219d499de1aa3117a92016-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/305https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article presents the current data of history of polycystic ovary syndrome (PCOS) study. It contains studies of genetic susceptibility of PCOS, PCOS symptoms and connection with development of anxiety and depressive disorders. The article covers ethnic differences in the phenotypic manifestations of PCOS. The papers describes the study of endocrine causes of infertility in Russian and Buryat women. Several theories of PCOS, including the theory of PCOS connection with intestinal bacterial flora disorders ("dysbiotic intestinal microbiota") are being discussed. The article also provides an overview of various scientific research in this area and the data of the relationship of PCOS and the risk of cardiometabolic disorders, insulin resistance, metabolic syndrome, obesity and sleep apnea. It highlights modern aspects in the study of PCOS etiology - studies of adipose tissue as an endocrine organ. The article reflects study of PCOS relationship with the level of the gastrointestinal tract hormones: leptin, insulin, ghrelin, cholecystokinin, peptide YY. The effect of short-term low-dose hormonal contraceptives on appetite levels in PCOS is covered. The scientific articles on the severity of hypertension in menopausal women with PCOS history and the presence of overweight are reviewed. The scientific work determines molecular genetic markers of PCOS in the aspect of the influence of environmental factors on the expression of genes.L. V. DamdinovaO. Ya. LeshchenkoScientific Сentre for Family Health and Human Reproduction Problemsarticlepcosstein-leventhal syndromeinfertilityoligomenorrheainsulin resistancehyperandrogenismhirsutismpolycystic ovariesintestinal microbiotaScienceQRUActa Biomedica Scientifica, Vol 1, Iss 5, Pp 181-186 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	pcos stein-leventhal syndrome infertility oligomenorrhea insulin resistance hyperandrogenism hirsutism polycystic ovaries intestinal microbiota Science Q
spellingShingle	pcos stein-leventhal syndrome infertility oligomenorrhea insulin resistance hyperandrogenism hirsutism polycystic ovaries intestinal microbiota Science Q L. V. Damdinova O. Ya. Leshchenko Polycystic ovary syndrome - 80 years of research and new directions in the study (literature review)
description	The article presents the current data of history of polycystic ovary syndrome (PCOS) study. It contains studies of genetic susceptibility of PCOS, PCOS symptoms and connection with development of anxiety and depressive disorders. The article covers ethnic differences in the phenotypic manifestations of PCOS. The papers describes the study of endocrine causes of infertility in Russian and Buryat women. Several theories of PCOS, including the theory of PCOS connection with intestinal bacterial flora disorders ("dysbiotic intestinal microbiota") are being discussed. The article also provides an overview of various scientific research in this area and the data of the relationship of PCOS and the risk of cardiometabolic disorders, insulin resistance, metabolic syndrome, obesity and sleep apnea. It highlights modern aspects in the study of PCOS etiology - studies of adipose tissue as an endocrine organ. The article reflects study of PCOS relationship with the level of the gastrointestinal tract hormones: leptin, insulin, ghrelin, cholecystokinin, peptide YY. The effect of short-term low-dose hormonal contraceptives on appetite levels in PCOS is covered. The scientific articles on the severity of hypertension in menopausal women with PCOS history and the presence of overweight are reviewed. The scientific work determines molecular genetic markers of PCOS in the aspect of the influence of environmental factors on the expression of genes.
format	article
author	L. V. Damdinova O. Ya. Leshchenko
author_facet	L. V. Damdinova O. Ya. Leshchenko
author_sort	L. V. Damdinova
title	Polycystic ovary syndrome - 80 years of research and new directions in the study (literature review)
title_short	Polycystic ovary syndrome - 80 years of research and new directions in the study (literature review)
title_full	Polycystic ovary syndrome - 80 years of research and new directions in the study (literature review)
title_fullStr	Polycystic ovary syndrome - 80 years of research and new directions in the study (literature review)
title_full_unstemmed	Polycystic ovary syndrome - 80 years of research and new directions in the study (literature review)
title_sort	polycystic ovary syndrome - 80 years of research and new directions in the study (literature review)
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/d4e5f80a771848219d499de1aa3117a9
work_keys_str_mv	AT lvdamdinova polycysticovarysyndrome80yearsofresearchandnewdirectionsinthestudyliteraturereview AT oyaleshchenko polycysticovarysyndrome80yearsofresearchandnewdirectionsinthestudyliteraturereview
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Polycystic ovary syndrome - 80 years of research and new directions in the study (literature review)

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