12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population
More than 170 genetic loci have been linked to prostate cancer risk, primarily based on genome-wide association studies (GWAS) in European population. Here, the authors performed a GWAS on a Japanese cohort of prostate cancer patients, finding 12 new susceptibility loci, and identifying a polygenic...
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/d4f4dad7d5aa4e5bbd57fba6d53b94a6 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:d4f4dad7d5aa4e5bbd57fba6d53b94a6 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:d4f4dad7d5aa4e5bbd57fba6d53b94a62021-12-02T17:31:53Z12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population10.1038/s41467-019-12267-62041-1723https://doaj.org/article/d4f4dad7d5aa4e5bbd57fba6d53b94a62019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12267-6https://doaj.org/toc/2041-1723More than 170 genetic loci have been linked to prostate cancer risk, primarily based on genome-wide association studies (GWAS) in European population. Here, the authors performed a GWAS on a Japanese cohort of prostate cancer patients, finding 12 new susceptibility loci, and identifying a polygenic risk for Japanese prostate cancer.Ryo TakataAtsushi TakahashiMasashi FujitaYukihide MomozawaEdward J. SaundersHiroki YamadaKazuhiro MaejimaKaoru NakanoYuichiro NishidaAsahi HishidaKeitaro MatsuoKenji WakaiTaiki YamajiNorie SawadaMotoki IwasakiShoichiro TsuganeMakoto SasakiAtsushi ShimizuKozo TannoNaoko MinegishiKichiya SuzukiKoichi MatsudaMichiaki KuboJohji InazawaShin EgawaChristopher A. HaimanOsamu OgawaWataru ObaraYoichiro KamataniShusuke AkamatsuHidewaki NakagawaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Ryo Takata Atsushi Takahashi Masashi Fujita Yukihide Momozawa Edward J. Saunders Hiroki Yamada Kazuhiro Maejima Kaoru Nakano Yuichiro Nishida Asahi Hishida Keitaro Matsuo Kenji Wakai Taiki Yamaji Norie Sawada Motoki Iwasaki Shoichiro Tsugane Makoto Sasaki Atsushi Shimizu Kozo Tanno Naoko Minegishi Kichiya Suzuki Koichi Matsuda Michiaki Kubo Johji Inazawa Shin Egawa Christopher A. Haiman Osamu Ogawa Wataru Obara Yoichiro Kamatani Shusuke Akamatsu Hidewaki Nakagawa 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population |
description |
More than 170 genetic loci have been linked to prostate cancer risk, primarily based on genome-wide association studies (GWAS) in European population. Here, the authors performed a GWAS on a Japanese cohort of prostate cancer patients, finding 12 new susceptibility loci, and identifying a polygenic risk for Japanese prostate cancer. |
format |
article |
author |
Ryo Takata Atsushi Takahashi Masashi Fujita Yukihide Momozawa Edward J. Saunders Hiroki Yamada Kazuhiro Maejima Kaoru Nakano Yuichiro Nishida Asahi Hishida Keitaro Matsuo Kenji Wakai Taiki Yamaji Norie Sawada Motoki Iwasaki Shoichiro Tsugane Makoto Sasaki Atsushi Shimizu Kozo Tanno Naoko Minegishi Kichiya Suzuki Koichi Matsuda Michiaki Kubo Johji Inazawa Shin Egawa Christopher A. Haiman Osamu Ogawa Wataru Obara Yoichiro Kamatani Shusuke Akamatsu Hidewaki Nakagawa |
author_facet |
Ryo Takata Atsushi Takahashi Masashi Fujita Yukihide Momozawa Edward J. Saunders Hiroki Yamada Kazuhiro Maejima Kaoru Nakano Yuichiro Nishida Asahi Hishida Keitaro Matsuo Kenji Wakai Taiki Yamaji Norie Sawada Motoki Iwasaki Shoichiro Tsugane Makoto Sasaki Atsushi Shimizu Kozo Tanno Naoko Minegishi Kichiya Suzuki Koichi Matsuda Michiaki Kubo Johji Inazawa Shin Egawa Christopher A. Haiman Osamu Ogawa Wataru Obara Yoichiro Kamatani Shusuke Akamatsu Hidewaki Nakagawa |
author_sort |
Ryo Takata |
title |
12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population |
title_short |
12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population |
title_full |
12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population |
title_fullStr |
12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population |
title_full_unstemmed |
12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population |
title_sort |
12 new susceptibility loci for prostate cancer identified by genome-wide association study in japanese population |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/d4f4dad7d5aa4e5bbd57fba6d53b94a6 |
work_keys_str_mv |
AT ryotakata 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT atsushitakahashi 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT masashifujita 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT yukihidemomozawa 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT edwardjsaunders 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT hirokiyamada 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT kazuhiromaejima 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT kaorunakano 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT yuichironishida 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT asahihishida 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT keitaromatsuo 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT kenjiwakai 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT taikiyamaji 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT noriesawada 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT motokiiwasaki 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT shoichirotsugane 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT makotosasaki 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT atsushishimizu 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT kozotanno 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT naokominegishi 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT kichiyasuzuki 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT koichimatsuda 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT michiakikubo 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT johjiinazawa 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT shinegawa 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT christopherahaiman 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT osamuogawa 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT wataruobara 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT yoichirokamatani 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT shusukeakamatsu 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation AT hidewakinakagawa 12newsusceptibilitylociforprostatecanceridentifiedbygenomewideassociationstudyinjapanesepopulation |
_version_ |
1718380459918884864 |