12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population

More than 170 genetic loci have been linked to prostate cancer risk, primarily based on genome-wide association studies (GWAS) in European population. Here, the authors performed a GWAS on a Japanese cohort of prostate cancer patients, finding 12 new susceptibility loci, and identifying a polygenic...

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Autores principales: Ryo Takata, Atsushi Takahashi, Masashi Fujita, Yukihide Momozawa, Edward J. Saunders, Hiroki Yamada, Kazuhiro Maejima, Kaoru Nakano, Yuichiro Nishida, Asahi Hishida, Keitaro Matsuo, Kenji Wakai, Taiki Yamaji, Norie Sawada, Motoki Iwasaki, Shoichiro Tsugane, Makoto Sasaki, Atsushi Shimizu, Kozo Tanno, Naoko Minegishi, Kichiya Suzuki, Koichi Matsuda, Michiaki Kubo, Johji Inazawa, Shin Egawa, Christopher A. Haiman, Osamu Ogawa, Wataru Obara, Yoichiro Kamatani, Shusuke Akamatsu, Hidewaki Nakagawa
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Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d4f4dad7d5aa4e5bbd57fba6d53b94a6
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spelling oai:doaj.org-article:d4f4dad7d5aa4e5bbd57fba6d53b94a62021-12-02T17:31:53Z12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population10.1038/s41467-019-12267-62041-1723https://doaj.org/article/d4f4dad7d5aa4e5bbd57fba6d53b94a62019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12267-6https://doaj.org/toc/2041-1723More than 170 genetic loci have been linked to prostate cancer risk, primarily based on genome-wide association studies (GWAS) in European population. Here, the authors performed a GWAS on a Japanese cohort of prostate cancer patients, finding 12 new susceptibility loci, and identifying a polygenic risk for Japanese prostate cancer.Ryo TakataAtsushi TakahashiMasashi FujitaYukihide MomozawaEdward J. SaundersHiroki YamadaKazuhiro MaejimaKaoru NakanoYuichiro NishidaAsahi HishidaKeitaro MatsuoKenji WakaiTaiki YamajiNorie SawadaMotoki IwasakiShoichiro TsuganeMakoto SasakiAtsushi ShimizuKozo TannoNaoko MinegishiKichiya SuzukiKoichi MatsudaMichiaki KuboJohji InazawaShin EgawaChristopher A. HaimanOsamu OgawaWataru ObaraYoichiro KamataniShusuke AkamatsuHidewaki NakagawaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ryo Takata
Atsushi Takahashi
Masashi Fujita
Yukihide Momozawa
Edward J. Saunders
Hiroki Yamada
Kazuhiro Maejima
Kaoru Nakano
Yuichiro Nishida
Asahi Hishida
Keitaro Matsuo
Kenji Wakai
Taiki Yamaji
Norie Sawada
Motoki Iwasaki
Shoichiro Tsugane
Makoto Sasaki
Atsushi Shimizu
Kozo Tanno
Naoko Minegishi
Kichiya Suzuki
Koichi Matsuda
Michiaki Kubo
Johji Inazawa
Shin Egawa
Christopher A. Haiman
Osamu Ogawa
Wataru Obara
Yoichiro Kamatani
Shusuke Akamatsu
Hidewaki Nakagawa
12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population
description More than 170 genetic loci have been linked to prostate cancer risk, primarily based on genome-wide association studies (GWAS) in European population. Here, the authors performed a GWAS on a Japanese cohort of prostate cancer patients, finding 12 new susceptibility loci, and identifying a polygenic risk for Japanese prostate cancer.
format article
author Ryo Takata
Atsushi Takahashi
Masashi Fujita
Yukihide Momozawa
Edward J. Saunders
Hiroki Yamada
Kazuhiro Maejima
Kaoru Nakano
Yuichiro Nishida
Asahi Hishida
Keitaro Matsuo
Kenji Wakai
Taiki Yamaji
Norie Sawada
Motoki Iwasaki
Shoichiro Tsugane
Makoto Sasaki
Atsushi Shimizu
Kozo Tanno
Naoko Minegishi
Kichiya Suzuki
Koichi Matsuda
Michiaki Kubo
Johji Inazawa
Shin Egawa
Christopher A. Haiman
Osamu Ogawa
Wataru Obara
Yoichiro Kamatani
Shusuke Akamatsu
Hidewaki Nakagawa
author_facet Ryo Takata
Atsushi Takahashi
Masashi Fujita
Yukihide Momozawa
Edward J. Saunders
Hiroki Yamada
Kazuhiro Maejima
Kaoru Nakano
Yuichiro Nishida
Asahi Hishida
Keitaro Matsuo
Kenji Wakai
Taiki Yamaji
Norie Sawada
Motoki Iwasaki
Shoichiro Tsugane
Makoto Sasaki
Atsushi Shimizu
Kozo Tanno
Naoko Minegishi
Kichiya Suzuki
Koichi Matsuda
Michiaki Kubo
Johji Inazawa
Shin Egawa
Christopher A. Haiman
Osamu Ogawa
Wataru Obara
Yoichiro Kamatani
Shusuke Akamatsu
Hidewaki Nakagawa
author_sort Ryo Takata
title 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population
title_short 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population
title_full 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population
title_fullStr 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population
title_full_unstemmed 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population
title_sort 12 new susceptibility loci for prostate cancer identified by genome-wide association study in japanese population
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d4f4dad7d5aa4e5bbd57fba6d53b94a6
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