CYTOKINE-PRODUCING POTENTIAL OF BLOOD CELLS AND SERUM CYTOKINES IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS

Abstract. Cytokine-producing potential of peripheral blood cells was determined as a stimulation index with polyclonal activators (i.e., a cytokine production ratio of stimulated versus resting cells), as well as concentrations of cytokines were investigated in blood serum of patients with chronic a...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	A. V. Sosnina, E. S. Mikhailova, A. I. Autenshlyus, N. A. Varaksin, N. A. Dotoleva, I. P. Mikhno, T. A. Ageeva, L. A. Shpagina
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	cytokine production atrophic gastritis dysplasia Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/d4fd449c4d214de89a5815f1625ca187
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d4fd449c4d214de89a5815f1625ca187
record_format	dspace
spelling	oai:doaj.org-article:d4fd449c4d214de89a5815f1625ca1872021-11-18T08:03:43ZCYTOKINE-PRODUCING POTENTIAL OF BLOOD CELLS AND SERUM CYTOKINES IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS1563-06252313-741X10.15789/1563-0625-2013-3-247-254https://doaj.org/article/d4fd449c4d214de89a5815f1625ca1872014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/632https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Cytokine-producing potential of peripheral blood cells was determined as a stimulation index with polyclonal activators (i.e., a cytokine production ratio of stimulated versus resting cells), as well as concentrations of cytokines were investigated in blood serum of patients with chronic atrophic gastritis. It was revealed that the stimulation indices concerning production of TNFα, IL-1β, IL-6, IL-8 and IL-10 by whole blood cells, along with serum concentrations of IL-8 and IL-18BP were increased in patients with epithelial dysplasia of stomach mucosa, as compared to patients without dysplasia. It was sahown, that the patients with higher polyclonal stimulation indices for IL-6 and IL-8 (resp., > 164 and > 38 arbitrary units) should be referred to a high-risk group for development of mucous epithelial dysplasia of stomach.A. V. SosninaE. S. MikhailovaA. I. AutenshlyusN. A. VaraksinN. A. DotolevaI. P. MikhnoT. A. AgeevaL. A. ShpaginaSPb RAACIarticlecytokine productionatrophic gastritisdysplasiaImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 15, Iss 3, Pp 247-254 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	cytokine production atrophic gastritis dysplasia Immunologic diseases. Allergy RC581-607
spellingShingle	cytokine production atrophic gastritis dysplasia Immunologic diseases. Allergy RC581-607 A. V. Sosnina E. S. Mikhailova A. I. Autenshlyus N. A. Varaksin N. A. Dotoleva I. P. Mikhno T. A. Ageeva L. A. Shpagina CYTOKINE-PRODUCING POTENTIAL OF BLOOD CELLS AND SERUM CYTOKINES IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS
description	Abstract. Cytokine-producing potential of peripheral blood cells was determined as a stimulation index with polyclonal activators (i.e., a cytokine production ratio of stimulated versus resting cells), as well as concentrations of cytokines were investigated in blood serum of patients with chronic atrophic gastritis. It was revealed that the stimulation indices concerning production of TNFα, IL-1β, IL-6, IL-8 and IL-10 by whole blood cells, along with serum concentrations of IL-8 and IL-18BP were increased in patients with epithelial dysplasia of stomach mucosa, as compared to patients without dysplasia. It was sahown, that the patients with higher polyclonal stimulation indices for IL-6 and IL-8 (resp., > 164 and > 38 arbitrary units) should be referred to a high-risk group for development of mucous epithelial dysplasia of stomach.
format	article
author	A. V. Sosnina E. S. Mikhailova A. I. Autenshlyus N. A. Varaksin N. A. Dotoleva I. P. Mikhno T. A. Ageeva L. A. Shpagina
author_facet	A. V. Sosnina E. S. Mikhailova A. I. Autenshlyus N. A. Varaksin N. A. Dotoleva I. P. Mikhno T. A. Ageeva L. A. Shpagina
author_sort	A. V. Sosnina
title	CYTOKINE-PRODUCING POTENTIAL OF BLOOD CELLS AND SERUM CYTOKINES IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS
title_short	CYTOKINE-PRODUCING POTENTIAL OF BLOOD CELLS AND SERUM CYTOKINES IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS
title_full	CYTOKINE-PRODUCING POTENTIAL OF BLOOD CELLS AND SERUM CYTOKINES IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS
title_fullStr	CYTOKINE-PRODUCING POTENTIAL OF BLOOD CELLS AND SERUM CYTOKINES IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS
title_full_unstemmed	CYTOKINE-PRODUCING POTENTIAL OF BLOOD CELLS AND SERUM CYTOKINES IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS
title_sort	cytokine-producing potential of blood cells and serum cytokines in patients with chronic atrophic gastritis
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/d4fd449c4d214de89a5815f1625ca187
work_keys_str_mv	AT avsosnina cytokineproducingpotentialofbloodcellsandserumcytokinesinpatientswithchronicatrophicgastritis AT esmikhailova cytokineproducingpotentialofbloodcellsandserumcytokinesinpatientswithchronicatrophicgastritis AT aiautenshlyus cytokineproducingpotentialofbloodcellsandserumcytokinesinpatientswithchronicatrophicgastritis AT navaraksin cytokineproducingpotentialofbloodcellsandserumcytokinesinpatientswithchronicatrophicgastritis AT nadotoleva cytokineproducingpotentialofbloodcellsandserumcytokinesinpatientswithchronicatrophicgastritis AT ipmikhno cytokineproducingpotentialofbloodcellsandserumcytokinesinpatientswithchronicatrophicgastritis AT taageeva cytokineproducingpotentialofbloodcellsandserumcytokinesinpatientswithchronicatrophicgastritis AT lashpagina cytokineproducingpotentialofbloodcellsandserumcytokinesinpatientswithchronicatrophicgastritis
_version_	1718422450266439680

CYTOKINE-PRODUCING POTENTIAL OF BLOOD CELLS AND SERUM CYTOKINES IN PATIENTS WITH CHRONIC ATROPHIC GASTRITIS

Ejemplares similares