Attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka

Thilak Priyantha Weerarathna,1 Herath Mudiyanselage Meththananda Herath,1 Gayani Liyanage,1 Miyuru Kavinda Weerarathna,2 Vidarsha Senadheera2 1Faculty of Medicine, University of Ruhuna, Matara, Sri Lanka; 2Faculty of Medicine, University of Colombo, Colombo, Sri Lanka Introduction: Implementation of...

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Autores principales:	Weerarathna TP, Herath HMM, Liyanage G, Weerarathna MK, Senadeera V
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Cardiovascular risk factors therapeutic targets Type 2 diabetes Sri Lanka Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/d4fe6704a2a7421e8840be5f35af9d8f
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spelling	oai:doaj.org-article:d4fe6704a2a7421e8840be5f35af9d8f2021-12-02T06:46:15ZAttainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka1178-7007https://doaj.org/article/d4fe6704a2a7421e8840be5f35af9d8f2018-08-01T00:00:00Zhttps://www.dovepress.com/attainment-of-recommended-therapeutic-targets-of-modifiable-cardiovasc-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Thilak Priyantha Weerarathna,1 Herath Mudiyanselage Meththananda Herath,1 Gayani Liyanage,1 Miyuru Kavinda Weerarathna,2 Vidarsha Senadheera2 1Faculty of Medicine, University of Ruhuna, Matara, Sri Lanka; 2Faculty of Medicine, University of Colombo, Colombo, Sri Lanka Introduction: Implementation of effective measures to control rising burden of cardiovascular diseases among patients with type 2 diabetes mellitus (T2DM) requires information on the adequacy of control and identification of specific groups with suboptimal control of blood glucose, lipids and blood pressure. Methods: A cross-sectional study of patients with T2DM referred from primary care to a diabetes center was carried out to estimate the proportion of patients achieving the recommended therapeutic targets of four major modifiable cardiovascular risk factors: glycosylated hemoglobin (HbA1c <7%), low-density lipoprotein cholesterol <100 mg/dL, systolic blood pressure (SBP) <130 mmHg and diastolic blood pressure (DBP) <80 mmHg and their associations with age, gender, duration of diabetes and body mass index were studied. Results: Mean (SD) age and the duration of the sample of 2422 (65% males) were 52 (11) and 9 (3), respectively. Percentages with optimal HbA1c, low-density lipoprotein cholesterol, SBP and DBP were 25.2%, 24.3%, 32% and 56.7%, respectively. Only 2% had achieved optimal control of all four risk factors. Significantly higher percentages of males were having optimal HbA1C, SBP and DBP, and regression analysis revealed that male gender was significantly associated with optimal control of SBP. Conclusion: Control of cardiovascular risk diseases factors among patients with T2DM managed in the primary care settings needs further improvements in target achievement in all four modifiable risk factors. Keywords: suboptimal control, therapeutic targets, type 2 diabetes mellitus, Sri LankaWeerarathna TPHerath HMMLiyanage GWeerarathna MKSenadeera VDove Medical PressarticleCardiovascular risk factorstherapeutic targetsType 2 diabetesSri LankaSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 11, Pp 409-415 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Cardiovascular risk factors therapeutic targets Type 2 diabetes Sri Lanka Specialties of internal medicine RC581-951
spellingShingle	Cardiovascular risk factors therapeutic targets Type 2 diabetes Sri Lanka Specialties of internal medicine RC581-951 Weerarathna TP Herath HMM Liyanage G Weerarathna MK Senadeera V Attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka
description	Thilak Priyantha Weerarathna,1 Herath Mudiyanselage Meththananda Herath,1 Gayani Liyanage,1 Miyuru Kavinda Weerarathna,2 Vidarsha Senadheera2 1Faculty of Medicine, University of Ruhuna, Matara, Sri Lanka; 2Faculty of Medicine, University of Colombo, Colombo, Sri Lanka Introduction: Implementation of effective measures to control rising burden of cardiovascular diseases among patients with type 2 diabetes mellitus (T2DM) requires information on the adequacy of control and identification of specific groups with suboptimal control of blood glucose, lipids and blood pressure. Methods: A cross-sectional study of patients with T2DM referred from primary care to a diabetes center was carried out to estimate the proportion of patients achieving the recommended therapeutic targets of four major modifiable cardiovascular risk factors: glycosylated hemoglobin (HbA1c <7%), low-density lipoprotein cholesterol <100 mg/dL, systolic blood pressure (SBP) <130 mmHg and diastolic blood pressure (DBP) <80 mmHg and their associations with age, gender, duration of diabetes and body mass index were studied. Results: Mean (SD) age and the duration of the sample of 2422 (65% males) were 52 (11) and 9 (3), respectively. Percentages with optimal HbA1c, low-density lipoprotein cholesterol, SBP and DBP were 25.2%, 24.3%, 32% and 56.7%, respectively. Only 2% had achieved optimal control of all four risk factors. Significantly higher percentages of males were having optimal HbA1C, SBP and DBP, and regression analysis revealed that male gender was significantly associated with optimal control of SBP. Conclusion: Control of cardiovascular risk diseases factors among patients with T2DM managed in the primary care settings needs further improvements in target achievement in all four modifiable risk factors. Keywords: suboptimal control, therapeutic targets, type 2 diabetes mellitus, Sri Lanka
format	article
author	Weerarathna TP Herath HMM Liyanage G Weerarathna MK Senadeera V
author_facet	Weerarathna TP Herath HMM Liyanage G Weerarathna MK Senadeera V
author_sort	Weerarathna TP
title	Attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka
title_short	Attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka
title_full	Attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka
title_fullStr	Attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka
title_full_unstemmed	Attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka
title_sort	attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in sri lanka
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/d4fe6704a2a7421e8840be5f35af9d8f
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Attainment of recommended therapeutic targets of modifiable cardiovascular risk factors among individuals with type 2 diabetes mellitus screened at a diabetes clinic in Sri Lanka

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