Minutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy

High resolution imaging of large biological volumes typically takes a long time from hours to days. Here the authors use a Bessel light-sheet approach combined with a content-aware compressed sensing computational pipeline to image whole mouse organs at subcellular resolution in a few minutes.

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Autores principales:	Chunyu Fang, Tingting Yu, Tingting Chu, Wenyang Feng, Fang Zhao, Xuechun Wang, Yujie Huang, Yusha Li, Peng Wan, Wei Mei, Dan Zhu, Peng Fei
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d5104ff62b3c45389281ea4bdc046fe8
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spelling	oai:doaj.org-article:d5104ff62b3c45389281ea4bdc046fe82021-12-02T15:08:00ZMinutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy10.1038/s41467-020-20329-32041-1723https://doaj.org/article/d5104ff62b3c45389281ea4bdc046fe82021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20329-3https://doaj.org/toc/2041-1723High resolution imaging of large biological volumes typically takes a long time from hours to days. Here the authors use a Bessel light-sheet approach combined with a content-aware compressed sensing computational pipeline to image whole mouse organs at subcellular resolution in a few minutes.Chunyu FangTingting YuTingting ChuWenyang FengFang ZhaoXuechun WangYujie HuangYusha LiPeng WanWei MeiDan ZhuPeng FeiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chunyu Fang Tingting Yu Tingting Chu Wenyang Feng Fang Zhao Xuechun Wang Yujie Huang Yusha Li Peng Wan Wei Mei Dan Zhu Peng Fei Minutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy
description	High resolution imaging of large biological volumes typically takes a long time from hours to days. Here the authors use a Bessel light-sheet approach combined with a content-aware compressed sensing computational pipeline to image whole mouse organs at subcellular resolution in a few minutes.
format	article
author	Chunyu Fang Tingting Yu Tingting Chu Wenyang Feng Fang Zhao Xuechun Wang Yujie Huang Yusha Li Peng Wan Wei Mei Dan Zhu Peng Fei
author_facet	Chunyu Fang Tingting Yu Tingting Chu Wenyang Feng Fang Zhao Xuechun Wang Yujie Huang Yusha Li Peng Wan Wei Mei Dan Zhu Peng Fei
author_sort	Chunyu Fang
title	Minutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy
title_short	Minutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy
title_full	Minutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy
title_fullStr	Minutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy
title_full_unstemmed	Minutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy
title_sort	minutes-timescale 3d isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d5104ff62b3c45389281ea4bdc046fe8
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Minutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy

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