Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies

Visweswara Rao Pasupuleti,1 TNVKV Prasad,2 Rayees Ahmad Shiekh,3 Satheesh Krishna Balam,4 Ganapathi Narasimhulu,5 Cirandur Suresh Reddy,4 Ismail Ab Rahman,3 Siew Hua Gan1 1Human Genome Center, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 2Institute of Fro...

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Autores principales:	Pasupuleti VR, Prasad TNVKV, Shiekh RA, Balam SK, Narasimhulu G, Reddy CS, Rahman IA, Gan SH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d514c81b35984a9baa88b4139ac7871a
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spelling	oai:doaj.org-article:d514c81b35984a9baa88b4139ac7871a2021-12-02T02:17:13ZBiogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies1176-91141178-2013https://doaj.org/article/d514c81b35984a9baa88b4139ac7871a2013-09-01T00:00:00Zhttp://www.dovepress.com/biogenic-silver-nanoparticles-using-rhinacanthus-nasutus-leaf-extract--a14248https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Visweswara Rao Pasupuleti,1 TNVKV Prasad,2 Rayees Ahmad Shiekh,3 Satheesh Krishna Balam,4 Ganapathi Narasimhulu,5 Cirandur Suresh Reddy,4 Ismail Ab Rahman,3 Siew Hua Gan1 1Human Genome Center, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 2Institute of Frontier Technology, Regional Agricultural Research Station, Acharya NG Ranga Agricultural University, Tirupati, Andhra Pradesh, India; 3Biomaterial Research Unit, School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 4Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh, India; 5Pharmacology and Toxicology, Faculty of Pharmacy, University of Technology Mara, Malaysia Abstract: Nanotechnology is gaining momentum due to its ability to transform metals into nanoparticles. The synthesis, characterization, and applications of biologically synthesized nanomaterials have become an important branch of nanotechnology. Plant extracts are a cost-effective, ecologically friendly, and efficient alternative for the large-scale synthesis of nanoparticles. In this study, silver nanoparticles (AgNps) were synthesized using Rhinacanthus nasutus leaf extract. After exposing the silver ions to the leaf extract, the rapid reduction of silver ions led to the formation of AgNps in solution. The synthesis was confirmed by ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy, and transmission electron microscopy. The in vitro antimicrobial activity of the AgNps synthesized using R. nasutus leaf extract was investigated against Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli, Aspergillus niger, and Aspergillus flavus using a disc diffusion method. The AgNps showed potential activity against all of the bacterial strains and fungal colonies, indicating that R. nasutus has the potential to be used in the development of value-added products in the biomedical and nanotechnology-based industries. Keywords: R. nasutus, silver nanoparticles, TEM, antimicrobial activitiesPasupuleti VRPrasad TNVKVShiekh RABalam SKNarasimhulu GReddy CSRahman IAGan SHDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2013, Iss default, Pp 3355-3364 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Pasupuleti VR Prasad TNVKV Shiekh RA Balam SK Narasimhulu G Reddy CS Rahman IA Gan SH Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies
description	Visweswara Rao Pasupuleti,1 TNVKV Prasad,2 Rayees Ahmad Shiekh,3 Satheesh Krishna Balam,4 Ganapathi Narasimhulu,5 Cirandur Suresh Reddy,4 Ismail Ab Rahman,3 Siew Hua Gan1 1Human Genome Center, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 2Institute of Frontier Technology, Regional Agricultural Research Station, Acharya NG Ranga Agricultural University, Tirupati, Andhra Pradesh, India; 3Biomaterial Research Unit, School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 4Department of Chemistry, Sri Venkateswara University, Tirupati, Andhra Pradesh, India; 5Pharmacology and Toxicology, Faculty of Pharmacy, University of Technology Mara, Malaysia Abstract: Nanotechnology is gaining momentum due to its ability to transform metals into nanoparticles. The synthesis, characterization, and applications of biologically synthesized nanomaterials have become an important branch of nanotechnology. Plant extracts are a cost-effective, ecologically friendly, and efficient alternative for the large-scale synthesis of nanoparticles. In this study, silver nanoparticles (AgNps) were synthesized using Rhinacanthus nasutus leaf extract. After exposing the silver ions to the leaf extract, the rapid reduction of silver ions led to the formation of AgNps in solution. The synthesis was confirmed by ultraviolet-visible spectroscopy, Fourier transform infrared spectroscopy, and transmission electron microscopy. The in vitro antimicrobial activity of the AgNps synthesized using R. nasutus leaf extract was investigated against Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli, Aspergillus niger, and Aspergillus flavus using a disc diffusion method. The AgNps showed potential activity against all of the bacterial strains and fungal colonies, indicating that R. nasutus has the potential to be used in the development of value-added products in the biomedical and nanotechnology-based industries. Keywords: R. nasutus, silver nanoparticles, TEM, antimicrobial activities
format	article
author	Pasupuleti VR Prasad TNVKV Shiekh RA Balam SK Narasimhulu G Reddy CS Rahman IA Gan SH
author_facet	Pasupuleti VR Prasad TNVKV Shiekh RA Balam SK Narasimhulu G Reddy CS Rahman IA Gan SH
author_sort	Pasupuleti VR
title	Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies
title_short	Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies
title_full	Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies
title_fullStr	Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies
title_full_unstemmed	Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies
title_sort	biogenic silver nanoparticles using rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/d514c81b35984a9baa88b4139ac7871a
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Biogenic silver nanoparticles using Rhinacanthus nasutus leaf extract: synthesis, spectral analysis, and antimicrobial studies

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