The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction

Co-infections with Pseudomonas aeruginosa and Staphylococcus aureus are common in cystic fibrosis patients. Here, the authors show that metal depletion induced by a host protein, calprotectin, promotes co-existence of both pathogens by inhibiting production of anti-staphylococcal molecules by P. aer...

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Autores principales:	Catherine A. Wakeman, Jessica L. Moore, Michael J. Noto, Yaofang Zhang, Marc D. Singleton, Boone M. Prentice, Benjamin A. Gilston, Ryan S. Doster, Jennifer A. Gaddy, Walter J. Chazin, Richard M. Caprioli, Eric P. Skaar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d51f678c97f6455c944b4d671341e53f
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spelling	oai:doaj.org-article:d51f678c97f6455c944b4d671341e53f2021-12-02T14:38:56ZThe innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction10.1038/ncomms119512041-1723https://doaj.org/article/d51f678c97f6455c944b4d671341e53f2016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11951https://doaj.org/toc/2041-1723Co-infections with Pseudomonas aeruginosa and Staphylococcus aureus are common in cystic fibrosis patients. Here, the authors show that metal depletion induced by a host protein, calprotectin, promotes co-existence of both pathogens by inhibiting production of anti-staphylococcal molecules by P. aeruginosa.Catherine A. WakemanJessica L. MooreMichael J. NotoYaofang ZhangMarc D. SingletonBoone M. PrenticeBenjamin A. GilstonRyan S. DosterJennifer A. GaddyWalter J. ChazinRichard M. CaprioliEric P. SkaarNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Catherine A. Wakeman Jessica L. Moore Michael J. Noto Yaofang Zhang Marc D. Singleton Boone M. Prentice Benjamin A. Gilston Ryan S. Doster Jennifer A. Gaddy Walter J. Chazin Richard M. Caprioli Eric P. Skaar The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction
description	Co-infections with Pseudomonas aeruginosa and Staphylococcus aureus are common in cystic fibrosis patients. Here, the authors show that metal depletion induced by a host protein, calprotectin, promotes co-existence of both pathogens by inhibiting production of anti-staphylococcal molecules by P. aeruginosa.
format	article
author	Catherine A. Wakeman Jessica L. Moore Michael J. Noto Yaofang Zhang Marc D. Singleton Boone M. Prentice Benjamin A. Gilston Ryan S. Doster Jennifer A. Gaddy Walter J. Chazin Richard M. Caprioli Eric P. Skaar
author_facet	Catherine A. Wakeman Jessica L. Moore Michael J. Noto Yaofang Zhang Marc D. Singleton Boone M. Prentice Benjamin A. Gilston Ryan S. Doster Jennifer A. Gaddy Walter J. Chazin Richard M. Caprioli Eric P. Skaar
author_sort	Catherine A. Wakeman
title	The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction
title_short	The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction
title_full	The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction
title_fullStr	The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction
title_full_unstemmed	The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction
title_sort	innate immune protein calprotectin promotes pseudomonas aeruginosa and staphylococcus aureus interaction
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/d51f678c97f6455c944b4d671341e53f
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The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction

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