RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA

Código QR

RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA

A central antiviral defence is immune recognition of cystolic DNA. Here the authors show that RPA and RAD51, in cooperation with TREX1, function to protect the cytosol from self-DNA.

Guardado en:

Detalles Bibliográficos
Autores principales:	Christine Wolf, Alexander Rapp, Nicole Berndt, Wolfgang Staroske, Max Schuster, Manuela Dobrick-Mattheuer, Stefanie Kretschmer, Nadja König, Thomas Kurth, Dagmar Wieczorek, Karin Kast, M. Cristina Cardoso, Claudia Günther, Min Ae Lee-Kirsch
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d52a3f8c27194a7f946279b592b29faa
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Descripción
Sumario:	A central antiviral defence is immune recognition of cystolic DNA. Here the authors show that RPA and RAD51, in cooperation with TREX1, function to protect the cytosol from self-DNA.