RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA

RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA

A central antiviral defence is immune recognition of cystolic DNA. Here the authors show that RPA and RAD51, in cooperation with TREX1, function to protect the cytosol from self-DNA.

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Detalles Bibliográficos
Autores principales: Christine Wolf, Alexander Rapp, Nicole Berndt, Wolfgang Staroske, Max Schuster, Manuela Dobrick-Mattheuer, Stefanie Kretschmer, Nadja König, Thomas Kurth, Dagmar Wieczorek, Karin Kast, M. Cristina Cardoso, Claudia Günther, Min Ae Lee-Kirsch
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/d52a3f8c27194a7f946279b592b29faa
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