Innovative High-Pressure Fabrication Processes for Porous Biomaterials—A Review

Biomaterials and their clinical application have become well known in recent years and progress in their manufacturing processes are essential steps in their technological advancement. Great advances have been made in the field of biomaterials, including ceramics, glasses, polymers, composites, glas...

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Autores principales: Mythili Prakasam, Jean-François Silvain, Alain Largeteau
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Lenguaje:EN
Publicado: MDPI AG 2021
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spelling oai:doaj.org-article:d52a7231694b463da5aafe5fb85509712021-11-25T16:46:32ZInnovative High-Pressure Fabrication Processes for Porous Biomaterials—A Review10.3390/bioengineering81101702306-5354https://doaj.org/article/d52a7231694b463da5aafe5fb85509712021-11-01T00:00:00Zhttps://www.mdpi.com/2306-5354/8/11/170https://doaj.org/toc/2306-5354Biomaterials and their clinical application have become well known in recent years and progress in their manufacturing processes are essential steps in their technological advancement. Great advances have been made in the field of biomaterials, including ceramics, glasses, polymers, composites, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applications of bioceramics include bone grafts, spinal fusion, bone repairs, bone fillers, maxillofacial reconstruction, etc. One of the common impediments in the bioceramics and metallic porous implants for biomedical applications are their lack of mechanical strength. High-pressure processing can be a viable solution in obtaining porous biomaterials. Many properties such as mechanical properties, non-toxicity, surface modification, degradation rate, biocompatibility, corrosion rate and scaffold design are taken into consideration. The current review focuses on different manufacturing processes used for bioceramics, polymers and metals and their alloys in porous forms. Recent advances in the manufacturing technologies of porous ceramics by freeze isostatic pressure and hydrothermal processing are discussed in detail. Pressure as a parameter can be helpful in obtaining porous forms for biomaterials with increased mechanical strength.Mythili PrakasamJean-François SilvainAlain LargeteauMDPI AGarticlebioceramicsmetallic implantsbiodegradable polymersporous biomaterialshigh pressure processingfreeze isostatic pressureTechnologyTBiology (General)QH301-705.5ENBioengineering, Vol 8, Iss 170, p 170 (2021)
institution DOAJ
collection DOAJ
language EN
topic bioceramics
metallic implants
biodegradable polymers
porous biomaterials
high pressure processing
freeze isostatic pressure
Technology
T
Biology (General)
QH301-705.5
spellingShingle bioceramics
metallic implants
biodegradable polymers
porous biomaterials
high pressure processing
freeze isostatic pressure
Technology
T
Biology (General)
QH301-705.5
Mythili Prakasam
Jean-François Silvain
Alain Largeteau
Innovative High-Pressure Fabrication Processes for Porous Biomaterials—A Review
description Biomaterials and their clinical application have become well known in recent years and progress in their manufacturing processes are essential steps in their technological advancement. Great advances have been made in the field of biomaterials, including ceramics, glasses, polymers, composites, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applications of bioceramics include bone grafts, spinal fusion, bone repairs, bone fillers, maxillofacial reconstruction, etc. One of the common impediments in the bioceramics and metallic porous implants for biomedical applications are their lack of mechanical strength. High-pressure processing can be a viable solution in obtaining porous biomaterials. Many properties such as mechanical properties, non-toxicity, surface modification, degradation rate, biocompatibility, corrosion rate and scaffold design are taken into consideration. The current review focuses on different manufacturing processes used for bioceramics, polymers and metals and their alloys in porous forms. Recent advances in the manufacturing technologies of porous ceramics by freeze isostatic pressure and hydrothermal processing are discussed in detail. Pressure as a parameter can be helpful in obtaining porous forms for biomaterials with increased mechanical strength.
format article
author Mythili Prakasam
Jean-François Silvain
Alain Largeteau
author_facet Mythili Prakasam
Jean-François Silvain
Alain Largeteau
author_sort Mythili Prakasam
title Innovative High-Pressure Fabrication Processes for Porous Biomaterials—A Review
title_short Innovative High-Pressure Fabrication Processes for Porous Biomaterials—A Review
title_full Innovative High-Pressure Fabrication Processes for Porous Biomaterials—A Review
title_fullStr Innovative High-Pressure Fabrication Processes for Porous Biomaterials—A Review
title_full_unstemmed Innovative High-Pressure Fabrication Processes for Porous Biomaterials—A Review
title_sort innovative high-pressure fabrication processes for porous biomaterials—a review
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/d52a7231694b463da5aafe5fb8550971
work_keys_str_mv AT mythiliprakasam innovativehighpressurefabricationprocessesforporousbiomaterialsareview
AT jeanfrancoissilvain innovativehighpressurefabricationprocessesforporousbiomaterialsareview
AT alainlargeteau innovativehighpressurefabricationprocessesforporousbiomaterialsareview
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