The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study

Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the intestinal tract and is associated with decreased bone mineral density. IBD patients are at higher risk of osteopenia, osteoporosis and fracture compared to non-IBD patients. The impact of IBD on the performance of orth...

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Autores principales:	Meghan M. Moran, Peter Wessman, Ola Rolfson, Daniel D. Bohl, Johan Kärrholm, Ali Keshavarzian, D. Rick Sumner
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d52c83a94c5946ffb0c604989c987f40
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spelling	oai:doaj.org-article:d52c83a94c5946ffb0c604989c987f402021-11-11T07:14:42ZThe risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study1932-6203https://doaj.org/article/d52c83a94c5946ffb0c604989c987f402021-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8568118/?tool=EBIhttps://doaj.org/toc/1932-6203Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the intestinal tract and is associated with decreased bone mineral density. IBD patients are at higher risk of osteopenia, osteoporosis and fracture compared to non-IBD patients. The impact of IBD on the performance of orthopedic implants has not been well studied. We hypothesized that a history of IBD at the time of primary total hip arthroplasty (THA) would increase the risk of subsequent failure as assessed by revision surgery. A retrospective implant survival analysis was completed using the Swedish Hip Arthroplasty Registry and the Sweden National Patient Register. A total of 150,073 patients undergoing THA for osteoarthritis within an 18-year period were included in the study. THA patients with (n = 2,604) and without (n = 147,469) a history of IBD at the time of THA were compared with primary revision as the main endpoint and adjusted using sex, age category and comorbidity (Elixhauser scores) as covariates. We found that patients with a history of IBD had a relatively higher risk of revision surgery for septic causes while the non-IBD patients had a relatively higher risk of revision for aseptic causes (p = 0.004). Our findings suggest there may be an association between gut health and THA performance.Meghan M. MoranPeter WessmanOla RolfsonDaniel D. BohlJohan KärrholmAli KeshavarzianD. Rick SumnerPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Meghan M. Moran Peter Wessman Ola Rolfson Daniel D. Bohl Johan Kärrholm Ali Keshavarzian D. Rick Sumner The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study
description	Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the intestinal tract and is associated with decreased bone mineral density. IBD patients are at higher risk of osteopenia, osteoporosis and fracture compared to non-IBD patients. The impact of IBD on the performance of orthopedic implants has not been well studied. We hypothesized that a history of IBD at the time of primary total hip arthroplasty (THA) would increase the risk of subsequent failure as assessed by revision surgery. A retrospective implant survival analysis was completed using the Swedish Hip Arthroplasty Registry and the Sweden National Patient Register. A total of 150,073 patients undergoing THA for osteoarthritis within an 18-year period were included in the study. THA patients with (n = 2,604) and without (n = 147,469) a history of IBD at the time of THA were compared with primary revision as the main endpoint and adjusted using sex, age category and comorbidity (Elixhauser scores) as covariates. We found that patients with a history of IBD had a relatively higher risk of revision surgery for septic causes while the non-IBD patients had a relatively higher risk of revision for aseptic causes (p = 0.004). Our findings suggest there may be an association between gut health and THA performance.
format	article
author	Meghan M. Moran Peter Wessman Ola Rolfson Daniel D. Bohl Johan Kärrholm Ali Keshavarzian D. Rick Sumner
author_facet	Meghan M. Moran Peter Wessman Ola Rolfson Daniel D. Bohl Johan Kärrholm Ali Keshavarzian D. Rick Sumner
author_sort	Meghan M. Moran
title	The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study
title_short	The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study
title_full	The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study
title_fullStr	The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study
title_full_unstemmed	The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study
title_sort	risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/d52c83a94c5946ffb0c604989c987f40
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The risk of revision following total hip arthroplasty in patients with inflammatory bowel disease, a registry based study

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