A network property necessary for concentration robustness

Absolute concentration robustness (ACR), independence of the steady-state concentration of a molecule from the environment, is difficult to predict. Here, the authors derive a network structure-based necessary condition for ACR, and suggest that metabolites satisfying the condition are prevalent.

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Autores principales:	Jeanne M. O. Eloundou-Mbebi, Anika Küken, Nooshin Omranian, Sabrina Kleessen, Jost Neigenfind, Georg Basler, Zoran Nikoloski
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d52efcbc23e04b40901b5f1b823304ff
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spelling	oai:doaj.org-article:d52efcbc23e04b40901b5f1b823304ff2021-12-02T15:34:09ZA network property necessary for concentration robustness10.1038/ncomms132552041-1723https://doaj.org/article/d52efcbc23e04b40901b5f1b823304ff2016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13255https://doaj.org/toc/2041-1723Absolute concentration robustness (ACR), independence of the steady-state concentration of a molecule from the environment, is difficult to predict. Here, the authors derive a network structure-based necessary condition for ACR, and suggest that metabolites satisfying the condition are prevalent.Jeanne M. O. Eloundou-MbebiAnika KükenNooshin OmranianSabrina KleessenJost NeigenfindGeorg BaslerZoran NikoloskiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jeanne M. O. Eloundou-Mbebi Anika Küken Nooshin Omranian Sabrina Kleessen Jost Neigenfind Georg Basler Zoran Nikoloski A network property necessary for concentration robustness
description	Absolute concentration robustness (ACR), independence of the steady-state concentration of a molecule from the environment, is difficult to predict. Here, the authors derive a network structure-based necessary condition for ACR, and suggest that metabolites satisfying the condition are prevalent.
format	article
author	Jeanne M. O. Eloundou-Mbebi Anika Küken Nooshin Omranian Sabrina Kleessen Jost Neigenfind Georg Basler Zoran Nikoloski
author_facet	Jeanne M. O. Eloundou-Mbebi Anika Küken Nooshin Omranian Sabrina Kleessen Jost Neigenfind Georg Basler Zoran Nikoloski
author_sort	Jeanne M. O. Eloundou-Mbebi
title	A network property necessary for concentration robustness
title_short	A network property necessary for concentration robustness
title_full	A network property necessary for concentration robustness
title_fullStr	A network property necessary for concentration robustness
title_full_unstemmed	A network property necessary for concentration robustness
title_sort	network property necessary for concentration robustness
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/d52efcbc23e04b40901b5f1b823304ff
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A network property necessary for concentration robustness

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